Protein Alignment CG3156 and Abcb1a

DIOPT Version :9

• Sequence 1: NP_569844.2
• Gene: CG3156 / 30994
• FlyBaseID: FBgn0023536
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_035206.2
• Gene: Abcb1a / 18671
• MGIID: 97570
• Length: 1276
• Species: Mus musculus
• Alignment Length: 641
• Identity: 226/641 - (35%)
• Similarity: 337/641 - (52%)
• Gaps: 69/641 - (10%)

  Fly    83 RNAKANLPTAVGAGIVPAPVKMGRSQYGRLLSLTKSEKWVLTAGIGCLVVSSAITMSVPLFLGKV 147
            ::.|.:...|:...:.||       .:.|:|.|..:|......||.|.:::..:..:..:...||
Mouse   674 QDRKLSTKEALDEDVPPA-------SFWRILKLNSTEWPYFVVGIFCAIINGGLQPAFSVIFSKV 731

  Fly   148 IDVVFN---------KSGMDSAAMAKLGEYSVLLFGIFVLGGFANFARVHLFGNAALRIVRSLRS 203
            :.|..|         .|.:.|.....||   ::.|..|.|.||.       ||.|...:.:.||.
Mouse   732 VGVFTNGGPPETQRQNSNLFSLLFLILG---IISFITFFLQGFT-------FGKAGEILTKRLRY 786

  Fly   204 RLYRSMLMQEVGWFD--TKGTGELINRLSNDTLMVGTSLSQNVSDGLRSVAMIGVGTGMMIYTSP 266
            .:::|||.|:|.|||  ...||.|..||:||...|..:....::...:::|.:|.|..:.:....
Mouse   787 MVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIFQNIANLGTGIIISLIYGW 851

  Fly   267 QLAAVSALVVP--AMAG---MAIVYGRYVRRITKVELDKYAEIMKFAEERFGNVKTVKTFCREQQ 326
            ||..:...:||  |:||   |.::.|:.::  .|.||:...   |.|.|...|.:||.:..|||:
Mouse   852 QLTLLLLAIVPIIAIAGVVEMKMLSGQALK--DKKELEGSG---KIATEAIENFRTVVSLTREQK 911

  Fly   327 EVAAFDGKLDEALQIGYKETRARAIFFGLTGFCGNFIIISVLYY---------GGTLVLQDSLTI 382
                |:....::|||.|:....:|..||:|     |.....:.|         |..||.|..:|.
Mouse   912 ----FETMYAQSLQIPYRNAMKKAHVFGIT-----FSFTQAMMYFSYAACFRFGAYLVTQQLMTF 967

  Fly   383 GALTAFMLYAGYV--AISMNGLSNFYSQLNKGIGASERIWEILDR--ECSIPIDKGVVP--LEKP 441
            .  ...::::..|  |:::..:|:|.....|...::..|..|:::  |......:|:.|  ||
Mouse   968 E--NVLLVFSAIVFGAMAVGQVSSFAPDYAKATVSASHIIRIIEKTPEIDSYSTQGLKPNMLE-- 1028

  Fly   442 VGEVGFQNVFFTFPTRPESAVLTDFSLNLMPGTTTAVVGRSGSGKTTIALLMLRLYDPQGGTVHL 506
             |.|.|..|.|.:||||...||...||.:..|.|.|:||.||.||:|:..|:.|.|||..|:|.|
Mouse  1029 -GNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFL 1092

  Fly   507 DGIDLRTVNPQWLRNNIGAVSQEPVLFSCSIRENILYGANPGETPSPERLQQVIEDANVSQFTDQ 571
            ||.:::.:|.||||..:|.|||||:||.|||.|||.||.| ....|.|.:.:..::||:.||.|.
Mouse  1093 DGKEIKQLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDN-SRVVSYEEIVRAAKEANIHQFIDS 1156

  Fly   572 LPDGLDTLVGQRGMMLSGGQKQRVAIARALIKNPAILILDEATSALDAVSENLVQNALDNLIQGR 636
            |||..:|.||.:|..||||||||:||||||::.|.||:|||||||||..||.:||.|||...:||
Mouse  1157 LPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGR 1221

  Fly   637 TVLTIAHRLSTIRNADQIAVLSDGKIVEQGSYNELMGIQEGVFRELVASQAFGSRN 692
            |.:.||||||||:|||.|.|:.:||:.|.|::.:|:. |:|::..:|:.||...|:
Mouse  1222 TCIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLA-QKGIYFSMVSVQAGAKRS 1276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3156	NP_569844.2	MdlB	106..687	CDD:224055	219/611 (36%)
		ABC_membrane	127..395	CDD:279056	76/292 (26%)
		ABC_MTABC3_MDL1_MDL2	447..686	CDD:213216	124/238 (52%)
Abcb1a	NP_035206.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		PTZ00265	47..1263	CDD:240339	222/626 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	646..681		1/6 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810