Protein Alignment CG3156 and Abcb4

DIOPT Version :10

• Sequence 1: NP_569844.2
• Gene: CG3156 / 30994
• FlyBaseID: FBgn0023536
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_032856.2
• Gene: Abcb4 / 18670
• MGIID: 97569
• Length: 1276
• Species: Mus musculus
• Alignment Length: 617
• Identity: 221/617 - (35%)
• Similarity: 329/617 - (53%)
• Gaps: 63/617 - (10%)

  Fly    92 AVGAGIVPAPVKMGRSQYGRLLSLTKSEKWVLTAGIGCLVVSSAITMSVPLFLGKVIDVVFNKSG 156
            |.|:|:   |:.|  ..:|.:     ::|:|...|...|.|:.:::|..|   |::::
Mouse    63 AHGSGL---PLMM--IVFGEM-----TDKFVDNTGNFSLPVNFSLSMLNP---GRILE------- 107

  Fly   157 MDSAAMAKLGEYSVLLFGIFVLGG---FANFARVHLFGNAALRIVRSLRSRLYRSMLMQEVGWFD 218
                  .::..|:....|   |||   .|.:.:|..:..||.|.::.:|.:.:.::|.||:||||
Mouse   108 ------EEMTRYAYYYSG---LGGGVLVAAYIQVSFWTLAAGRQIKKIRQKFFHAILRQEMGWFD 163

  Fly   219 TKGTGELINRLSNDTLMVGTSLSQNVSDGLRSVAMIGVGTGMMIYTSPQLAAVSALVVPAMAGMA 283
            .|||.||..||::|...:...:...|....:::|....|..:......:|..|...:.|.:....
Mouse   164 IKGTTELNTRLTDDVSKISEGIGDKVGMFFQAIATFFAGFIVGFIRGWKLTLVIMAISPILGLST 228

  Fly   284 IVYGRYVRRITKVELDKYAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIGYKETRA 348
            .|:.:.:...:..||..||:....|||..|.::||..|..:.:|:..:...|:.|.:||.|:..:
Mouse   229 AVWAKILSTFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKKIGIKKAIS 293

  Fly   349 RAIFFGLTGFCGNFIIISVLY-----YGGTLVLQDSLTIG-ALTAFM------LYAGYVAISMNG 401
            ..|..|:.     |::|...|     ||.|||:....||| |:|.|.      ...|..|..::.
Mouse   294 ANISMGIA-----FLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILIGAFSVGQAAPCIDA 353

  Fly   402 LSNFYSQLNKGIGASERIWEILDRECSIP--IDKGVVPLEKPVGEVGFQNVFFTFPTRPESAVLT 464
            .:|       ..||:..|::|:|....|.  .::|..| :...|.:.|.:|.|::|:|....:|.
Mouse   354 FAN-------ARGAAYVIFDIIDNNPKIDSFSERGHKP-DNIKGNLEFSDVHFSYPSRANIKILK 410

  Fly   465 DFSLNLMPGTTTAVVGRSGSGKTTIALLMLRLYDPQGGTVHLDGIDLRTVNPQWLRNNIGAVSQE 529
            ..:|.:..|.|.|:||.||.||:|...|:.|||||..|.:.:||.|:|..|.:.||..||.||||
Mouse   411 GLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGKISIDGQDIRNFNVRCLREIIGVVSQE 475

  Fly   530 PVLFSCSIRENILYGANPGETPSPERLQQVIEDANVSQFTDQLPDGLDTLVGQRGMMLSGGQKQR 594
            |||||.:|.|||.||..   ..:.:.:::.:::||...|..:||...|||||.||..||||||||
Mouse   476 PVLFSTTIAENIRYGRG---NVTMDEIEKAVKEANAYDFIMKLPQKFDTLVGDRGAQLSGGQKQR 537

  Fly   595 VAIARALIKNPAILILDEATSALDAVSENLVQNALDNLIQGRTVLTIAHRLSTIRNADQIAVLSD 659
            :||||||::||.||:|||||||||..||..||.|||...:|||.:.||||||||||||.||...|
Mouse   538 IAIARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTTIVIAHRLSTIRNADVIAGFED 602

  Fly   660 GKIVEQGSYNELMGIQEGVFRELVASQAFGSR 691
            |.||||||::|||. :||::..||..|..||:
Mouse   603 GVIVEQGSHSELMK-KEGIYFRLVNMQTAGSQ 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3156	NP_569844.2	MdlB	103..687	CDD:440747	214/600 (36%)
Abcb4	NP_032856.2	PTZ00265	30..1269	CDD:240339	221/617 (36%)
		MdlB	39..632	CDD:440747	219/614 (36%)
		Interaction with HAX1. /evidence=ECO:0000250	622..646		5/12 (42%)