Protein Alignment CG3156 and pgp-5

DIOPT Version :9

• Sequence 1: NP_569844.2
• Gene: CG3156 / 30994
• FlyBaseID: FBgn0023536
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_001257116.1
• Gene: pgp-5 / 181276
• WormBaseID: WBGene00003999
• Length: 1252
• Species: Caenorhabditis elegans
• Alignment Length: 615
• Identity: 205/615 - (33%)
• Similarity: 310/615 - (50%)
• Gaps: 77/615 - (12%)

  Fly   116 TKSEKWVLTAGIGCLVVSSAIT-MSVPL----------FLGKVIDVVFNKS--GMDSAAMAKLGE 167
            |:.||.:...|    ||.|.:| |..|.          .|.||.:.:.||:  .:|.|...||.|
 Worm    30 TRYEKLLFFLG----VVFSILTGMCQPFESYTLGETSQVLVKVTNAINNKTIDPVDLAHAYKLFE 90

  Fly   168 YS----VLLFGIFVLG------GFANFARVHLFG-NAALRIVRSLRSRLYRSMLMQEVGWFDTKG 221
            ..    ||||  |::|      ||..|:.:...| |.|..:.|...|||.|    :::.:||...
 Worm    91 SDMNRVVLLF--FLVGFAYFTFGFLQFSIMKFVGDNTAYNVRRQYISRLLR----KDISYFDGMS 149

  Fly   222 TGELINRLSNDTLMVGTSLSQNVSDGLRSVAMIGVGTGMMIYTSPQLAAVSAL----VVPAMAGM 282
            ||.|...|:::........::.::..:..:....:||.:..||..:||....:    :|  ::|:
 Worm   150 TGHLSIVLNDNMERFREVFNEKIALIIALLTDFVIGTILAFYTDWRLACYGTVFSFGIV--LSGL 212

  Fly   283 AIVYGRYVRRITKVELDKYAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIGYKETR 347
            ...:|:  .:..:.:.:..:.....|.:..|..|||.:...:||||..:    .|.|:.|.|...
 Worm   213 LDSWGK--MKNNEKQNEHISNAGSIAFQALGCYKTVSSLNGQQQEVERY----TEELKNGEKYAL 271

  Fly   348 ARAIFFGLTG----FCGNFIIISVLYYGGTLVLQDSLTIGALTAFMLYAGYVAISMNGLSNFYSQ 408
            .||..|.|:.    |..|.:...:||:|..::.:.::..|.:...:.|..:.:..:.......|:
 Worm   272 NRAFVFSLSRSADYFFTNALNFVILYFGANMIYEGTIEPGVVVRILYYILFGSYCLGEAILHISR 336

  Fly   409 LNKGIGASERIWEILDRECSIPIDKGVVPLE------KPV--GEVGFQNVFFTFPTRPESAVLTD 465
            |...|..:..|.:||       :|......|      |..  |.:.|:||.|::||||:..||.:
 Worm   337 LASAIPLTVPIADIL-------LDSDATADEFFSEEIKDTFQGIISFKNVLFSYPTRPDVPVLKE 394

  Fly   466 FSLNLMPGTTTAVVGRSGSGKTTIALLMLRLYDPQGGTVHLDGIDLRTVNPQWLRNNIGAVSQEP 530
            .|.|:..|...|:||.|||||:|:..|:|..|:...|.:.:||.|:..:|.:.||..:|.|.|||
 Worm   395 ISFNVQGGECIALVGASGSGKSTVIQLLLHYYNIDSGRISIDGNDIYNINIKQLRQAMGVVFQEP 459

  Fly   531 VLFSCSIRENILYGANPGETPSPERLQQVIED----ANVSQFTDQLPDGLDTLVGQRGMMLSGGQ 591
            |||:.||.|||.:|       .|:..:|.|.|    ||...|....|||:.|:||:||..|||||
 Worm   460 VLFNTSIEENIRFG-------KPDATEQEIIDALKNANAFDFVCNFPDGIKTIVGERGAQLSGGQ 517

  Fly   592 KQRVAIARALIKNPAILILDEATSALDAVSENLVQNALDNLIQGRTVLTIAHRLSTIRNADQIAV 656
            |||:||||.|::||.||:|||||||||..||.:||.||.....|||.:.:||||||||||::|.|
 Worm   518 KQRIAIARTLVRNPRILLLDEATSALDNESEFIVQEALQKASIGRTTIVVAHRLSTIRNANKIIV 582

  Fly   657 LSDGKIVEQGSYNELMGIQEGVFRELVASQ 686
            :..|:|||.|.:.:|:.: .||:..||.:|
 Worm   583 MEKGEIVEVGDHKQLIAM-NGVYNNLVQTQ 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3156	NP_569844.2	MdlB	106..687	CDD:224055	205/615 (33%)
		ABC_membrane	127..395	CDD:279056	72/299 (24%)
		ABC_MTABC3_MDL1_MDL2	447..686	CDD:213216	118/242 (49%)
pgp-5	NP_001257116.1	PTZ00265	27..1241	CDD:240339	205/615 (33%)
		ABC_membrane	41..322	CDD:294371	72/294 (24%)
		ABC_MTABC3_MDL1_MDL2	374..611	CDD:213216	118/244 (48%)
		ABC_membrane	688..955	CDD:294371
		ABC_MTABC3_MDL1_MDL2	1005..1243	CDD:213216

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	1	1.100	-	-	O	PTHR24221
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910