Protein Alignment CG3156 and pgp-2

DIOPT Version :9

• Sequence 1: NP_569844.2
• Gene: CG3156 / 30994
• FlyBaseID: FBgn0023536
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_001300410.1
• Gene: pgp-2 / 172262
• WormBaseID: WBGene00003996
• Length: 1296
• Species: Caenorhabditis elegans
• Alignment Length: 601
• Identity: 198/601 - (32%)
• Similarity: 305/601 - (50%)
• Gaps: 40/601 - (6%)

  Fly    94 GAGIVPAPVKMGRSQYGRLLSLTKSEKWVLTAGIGCLVVSSAITMSVPLFLGKVIDVVFNKSGMD 158
            |||.....:.:|    |......:::......|:..:.....:.:|:..|..:|:
 Worm    68 GAGFPLLAIVLG----GMTTVFLRAQNSDFVVGVDNVNPEGLVPISLDEFNSEVV---------- 118

  Fly   159 SAAMAKLGEYSVLLFGIFVLGGFANFARVHLFGNAALRIVRSLRSRLYRSMLMQEVGWFDTKGTG 223
                    :|.:....:.||..|.::.::..|.:.|.|:|..||....:::|.|::.|||.:.||
 Worm   119 --------KYCIYYLVLGVLMFFTSYVQIACFESYAERLVHKLRQNYLKAILRQQIQWFDKQQTG 175

  Fly   224 ELINRLSNDTLMVGTSLSQNVSDGLRSVAMIGVGTGMMIYTSPQLAAVSALVVPAMAGMAIVYGR 288
            .|..||::|...|...|....:..::..|....|.|:..:.|..:    .||:...|.:.::.|.
 Worm   176 NLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGVGFFYSWSM----TLVMMGFAPLIVLSGA 236

  Fly   289 YVRRI----TKVELDKYAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIGYKETRAR 349
            .:.:.    |:||.:.||.....|||.|.:::||.:....::|:..|...|:...|.|..:....
 Worm   237 KMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHSLNGHKRELDRFYNALEVGRQTGIVKYCYM 301

  Fly   350 AIFFGLTGFCGNFIIISVLYYGGTLVLQDSLTIGAL---TAFMLYAGYVAISMNGLSNFYSQLNK 411
            .|..|.:..|.........:||.||::.|......|   ..|.:.:|  :.|:.|.....:....
 Worm   302 GIGVGFSNLCMYSSYALAFWYGSTLIINDPTFDRGLIFTVFFAVLSG--STSLGGALPHLASFGT 364

  Fly   412 GIGASERIWEILDRECSI-PIDKGVVPLEKPVGEVGFQNVFFTFPTRPESAVLTDFSLNLMPGTT 475
            ..||:..:..:::....| |.....:.::...|::.|::|.|.:|:|.:..||...||.|..|..
 Worm   365 ARGAASTVLRVINSHPKIDPYSLEGILVDNMKGDISFKDVHFRYPSRKDIHVLKGISLELKAGDK 429

  Fly   476 TAVVGRSGSGKTTIALLMLRLYDPQGGTVHLDGIDLRTVNPQWLRNNIGAVSQEPVLFSCSIREN 540
            .|:||.||.||:||..|:.|.|||..|.|.:||:|||.||...||..||.||||||||..:|.||
 Worm   430 IALVGSSGCGKSTIVNLLQRFYDPTKGRVLIDGVDLREVNVHSLREQIGIVSQEPVLFDGTIYEN 494

  Fly   541 ILYGANPGETPSPERLQQVIEDANVSQFTDQLPDGLDTLVGQRGMMLSGGQKQRVAIARALIKNP 605
            |..|   .|..:.:::.:..:.||.:.|..:||||..|.||::|:.||||||||:||||||:|||
 Worm   495 IKMG---NEHATHDQVVEACKMANANDFIKRLPDGYGTRVGEKGVQLSGGQKQRIAIARALVKNP 556

  Fly   606 AILILDEATSALDAVSENLVQNALDNLIQGRTVLTIAHRLSTIRNADQIAVLSDGKIVEQGSYNE 670
            .||:|||||||||..:|..||.|||....|||.:.:|||||||||.|:|.|...|.|||.||:.|
 Worm   557 KILLLDEATSALDTEAEREVQGALDQAQAGRTTIIVAHRLSTIRNVDRIFVFKAGNIVESGSHEE 621

  Fly   671 LMGIQEGVFRELVASQ 686
            ||. ::|:|.::..:|
 Worm   622 LMS-KQGIFYDMTQAQ 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3156	NP_569844.2	MdlB	106..687	CDD:224055	194/589 (33%)
		ABC_membrane	127..395	CDD:279056	61/274 (22%)
		ABC_MTABC3_MDL1_MDL2	447..686	CDD:213216	123/238 (52%)
pgp-2	NP_001300410.1	PTZ00265	56..1286	CDD:240339	198/601 (33%)
		ABC_membrane	61..349	CDD:279056	67/308 (22%)
		ABC_MTABC3_MDL1_MDL2	399..632	CDD:213216	123/236 (52%)
		ABC_membrane	736..999	CDD:279056
		ABC_MTABC3_MDL1_MDL2	1052..1290	CDD:213216

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	1	1.100	-	-	O	PTHR24221
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910