DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3156 and tap1

DIOPT Version :9

Sequence 1:	NP_569844.2	Gene:	CG3156 / 30994	FlyBaseID:	FBgn0023536	Length:	692	Species:	Drosophila melanogaster
Sequence 2:	XP_002665053.1	Gene:	tap1 / 100333043	ZFINID:	ZDB-GENE-050517-43	Length:	731	Species:	Danio rerio

Alignment Length:	652	Identity:	212/652 - (32%)
Similarity:	347/652 - (53%)	Gaps:	36/652 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 HSHLHP------------TLRMPW-WCMRRGFAQSSKWLARNA---KANLPTAVGAGIVPAPVKM 104
            |..|:|            |:.:.| |...:|..|....|..:.   |.::||.:.........|.
Zfish    79 HGLLYPVYISFLWAYGWSTVELVWGWHSWQGLVQGYFVLGLSLLIWKRHVPTILLTAKKERTEKK 143

  Fly   105 GRSQYGRLLSLTKSEKWVLTAGIGCLVVSSAITMSVPLFLGKVIDVVFNKSGMDSAAMAKLGEYS 169
            |::...|||...|.......|....:|:||...|::|.:.||:.|.:.|:...::.      .::
Zfish   144 GKASLQRLLGYMKPFSGRFAAVFFFVVISSLGEMAIPHYTGKMTDWIMNEDEPEAF------NHA 202

  Fly   170 VLLFGIF-VLGGFANFARVHLFGNAALRIVRSLRSRLYRSMLMQEVGWFDTKGTGELINRLSNDT 233
            :.:..:. ::.....|....::.....||..|::..:::::|.|::.:||...||::::|::.||
Zfish   203 ITVMTLMTIMSAVCEFVCDLIYNITMSRIHTSIQGLVFQAVLKQDIAFFDKATTGDIVSRITTDT 267

  Fly   234 LMVGTSLSQNVS----DGLRSVAMIGVGTGMMIYTSPQLAAVSALVVPAMAGMAIVYGRYVRRIT 294
            ..:..|||:.:|    ..:|.:.:.    |.|:..|.:|...:.|.:|.:..:..::||:.::::
Zfish   268 NTMSESLSEKLSLLMWYFMRVIFLF----GSMLMLSTRLCCFTLLGLPVIWIIPEIFGRFYQKLS 328

  Fly   295 KVELDKYAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIGYKETRARAIFFGLTGFC 359
            ....|..|:..:.|.|.|.::|||::|..|..|...:...|::...:...|..|.|:........
Zfish   329 AQVQDSLAKANEVATETFSSMKTVRSFANEDGETERYRKCLEDTFALNKVEAAAYAVSTWTNSMS 393

  Fly   360 GNFIIISVLYYGGTLVLQDSLTIGALTAFMLYAGYVAISMNGLSNFYSQLNKGIGASERIWEILD 424
            ...:.:|:|||||.||....::.|.|.:|:||......::..|.:::..:.|.:||||:|:|.:|
Zfish   394 SLALKVSILYYGGRLVTGSDVSSGDLVSFVLYELQFTSAVEVLMSYWPHVKKAVGASEKIFEYVD 458

  Fly   425 RECSIPIDKGVVPLEKPVGEVGFQNVFFTFPTRPESAVLTDFSLNLMPGTTTAVVGRSGSGKTTI 489
            |:..:|.|..:.| :...|.|.|:||.|.:|.||::.||.:.||.|..|..||:||.|||||||:
Zfish   459 RKPDVPPDGSLAP-KTLKGHVQFRNVTFAYPKRPDTDVLKNVSLELKAGKITALVGPSGSGKTTV 522

  Fly   490 ALLMLRLYDPQGGTVHLDGIDLRTVNPQWLRNNIGAVSQEPVLFSCSIRENILYGANPGETPSPE 554
            ..|:.|.|.||.|.:.||...|.:...|:|...|..||||||||:.|:||||.||.   |..:.|
Zfish   523 VSLLERFYQPQNGEILLDQKPLLSYKDQYLHEKISVVSQEPVLFARSVRENIKYGK---ENATNE 584

  Fly   555 RLQQVIEDANVSQFTDQLPDGLDTLVGQRGMMLSGGQKQRVAIARALIKNPAILILDEATSALDA 619
            .:......||...|...||.|.||..|::|..:|||||||:|||||||:.|.||:||:|||:||.
Zfish   585 EIYAAARLANAHDFISSLPKGYDTDAGEKGGQVSGGQKQRIAIARALIQKPQILVLDDATSSLDT 649

  Fly   620 VSENLVQNALDNLIQGRTVLTIAHRLSTIRNADQIAVLSDGKIVEQGSYNELMGIQEGVFRELVA 684
            .||:.|.:||...:|..|||.|:||||.:.|||.|..|.:|::||:|::.:|:. ::|.:.|.|.
Zfish   650 ESEHRVYSALKKELQSCTVLLISHRLSGVENADHILFLREGELVEEGNHQQLLD-KQGFYAEFVK 713

  Fly   685 SQ 686
            .|
Zfish   714 QQ 715

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3156	NP_569844.2	MdlB	106..687	CDD:224055	198/586 (34%)
		ABC_membrane	127..395	CDD:279056	63/272 (23%)
		ABC_MTABC3_MDL1_MDL2	447..686	CDD:213216	114/238 (48%)
tap1	XP_002665053.1	3a01208	42..712	CDD:273363	210/647 (32%)
		ABC_membrane	166..433	CDD:279056	63/276 (23%)
		P-loop_NTPase	467..692	CDD:304359	110/228 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0058
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D684058at2759
OrthoFinder	1	1.000	-	-		FOG0000243
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820