Protein Alignment CG3156 and abcc1

DIOPT Version :9

• Sequence 1: NP_569844.2
• Gene: CG3156 / 30994
• FlyBaseID: FBgn0023536
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: XP_001341895.3
• Gene: abcc1 / 100002010
• ZFINID: ZDB-GENE-050517-15
• Length: 1518
• Species: Danio rerio
• Alignment Length: 649
• Identity: 167/649 - (25%)
• Similarity: 299/649 - (46%)
• Gaps: 79/649 - (12%)

  Fly    81 LARNAKANLPTAVGAGIV---------PAPVKMGRSQYGRLLSLTKSEK--------WVLTAGIG 128
            |.|.::.:| .|.|||..         .|..|...::..||....|:..        |.....||
Zfish   895 LLRQSQISL-NATGAGKTTQKTEANDDAAATKTKSAEASRLTEADKANTGRVKLSVFWEYMKAIG 958

  Fly   129 CLVVSSAITMSVPLF-------LGK-------VIDVVFNKSGMDSAAMAKLGEYSVLLF--GIFV 177
             |.:|   ..|:.||       ||.       ..|.|.|.:  ......:||.|..|..  ||.|
Zfish   959 -LPLS---IFSIFLFFCHHLSSLGSNYWLSLWTDDPVVNNT--QPKREMRLGVYGALGISQGIAV 1017

  Fly   178 LGGFANFARVHLFGNAALRIVRSLRSRLYRSMLMQEVGWFDTKGTGELINRLSNDTLMVGTSLSQ 242
               |.....|.:.|..|.|.:.  ::.|| ::|...:.:|:...:|.|:||.:.:|..:.:.:..
Zfish  1018 ---FCYSVSVSVGGILASRYLH--QTMLY-NVLRSPMSFFERTPSGNLVNRFAKETDTIDSVIPS 1076

  Fly   243 -------NVSDGLRSVAMIGVGTGMMIYTSPQLAAVSALVVPAMAGMAIVYGRYV----RRITKV 296
                   ::.:.|.|.|:|.:.|.::           |:::|.:..:.....|:.    |::.::
Zfish  1077 IIKMFMGSMFNVLGSCAVILIATPLV-----------AIIIPPLGLLYFFVQRFYVASSRQMKRL 1130

  Fly   297 ELDKYAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIGYKETRARAIFFGLTGFCGN 361
            |....:.:.....|.......::.|..:|:.:...||::|...:..:....|.........|.||
Zfish  1131 ESVSRSPVYTHFNETLLGTSVIRAFGEQQRFIKESDGRVDHNQKAYFPSIVANRWLAVRLEFVGN 1195

  Fly   362 FIIISVLYYGGTLVLQDSLTIGALTAFMLYAGYVAISMNGLSNFYSQLNKGIGASERIWEILD-- 424
            .|:.....:  .::.:::|:.|.:...:.||..|..|:|.|....|:|...|.|.||:.|..|
Zfish  1196 CIVTFAALF--AVMARNNLSPGIMGLSISYALQVTASLNWLVRMSSELETNIVAVERVKEYGDTE 1258

  Fly   425 RECSIPIDKGVVPLEKP-VGEVGFQNVFFTFPTRPESAVLTDFSLNLMPGTTTAVVGRSGSGKTT 488
            :|....::...:|...| .|.:........:....|.|: .|.|:|:..|....:|||:|:||::
Zfish  1259 KEAEWKLENSNLPPGWPTAGHIEIHKFGLRYREDLELAI-CDISVNIAGGEKVGIVGRTGAGKSS 1322

  Fly   489 IALLMLRLYDPQGGTVHLDGIDLRTVNPQWLRNNIGAVSQEPVLFSCSIRENILYGANPGETPSP 553
            :.|.:.|:.:...|.:.:||:::..:....||:.|..:.|:|||||.|:|.|:    :|.:..:.
Zfish  1323 LTLGLFRIIEAAEGEIRIDGVNIADLGLHELRSRITIIPQDPVLFSGSLRMNL----DPFDGYTD 1383

  Fly   554 ERLQQVIEDANVSQFTDQLPDGLDTLVGQRGMMLSGGQKQRVAIARALIKNPAILILDEATSALD 618
            |.:.:.:|.|::..|...|||.|:....:.|..||.||:|.|.:||||::...||:|||||:|:|
Zfish  1384 EEVWRSLELAHLKTFVSGLPDKLNHECSEGGENLSLGQRQLVCLARALLRKTKILVLDEATAAVD 1448

  Fly   619 AVSENLVQNALDNLIQGRTVLTIAHRLSTIRNADQIAVLSDGKIVEQGSYNELMGIQEGVFREL 682
            ..::||:|:.:....:..|||||||||:||.:..::.||..|::.|..|.:.|:. ::|:|.::
Zfish  1449 LETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVLVLDKGQMAEFDSPSNLIA-KKGIFYKM 1511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3156	NP_569844.2	MdlB	106..687	CDD:224055	158/615 (26%)
		ABC_membrane	127..395	CDD:279056	58/294 (20%)
		ABC_MTABC3_MDL1_MDL2	447..686	CDD:213216	80/236 (34%)
abcc1	XP_001341895.3	MRP_assoc_pro	7..1517	CDD:188098	167/649 (26%)
		ABC_membrane	331..595	CDD:279056
		ABCC_MRP_domain1	641..842	CDD:213217
		ABC_membrane	966..1231	CDD:279056	54/285 (19%)
		ABCC_MRP_domain2	1278..1498	CDD:213211	77/224 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000