DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4g1 and CYP86C1

DIOPT Version :9

Sequence 1:	NP_525031.1	Gene:	Cyp4g1 / 30986	FlyBaseID:	FBgn0010019	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_173862.1	Gene:	CYP86C1 / 839069	AraportID:	AT1G24540	Length:	522	Species:	Arabidopsis thaliana

Alignment Length:	590	Identity:	130/590 - (22%)
Similarity:	228/590 - (38%)	Gaps:	149/590 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LTTLVGTLVAMALYEYWRRNSREYRMVANIPSPPELPILGQAHVAAGLSNAEILAVGLGYLNKY- 91
            |:.:...||.:.|..|.|.     ::|:. ..|...|:||...:.|              |||:
plant    17 LSDVALALVGLFLLSYLRE-----KLVSK-GGPVMWPVLGIIPMLA--------------LNKHD 61

  Fly    92 ------------GETMK---AWLGNVLLVFLTNPSDIELIL-SGHQHLTKAEEYR-YFKPWFGDG 139
                        |.|..   .|.|....:...:|:::|.|| :..::..|...|| .|:....||
plant    62 LFTWCTRCVVRSGGTFHYRGIWFGGAYGIMTADPANVEHILKTNFKNYPKGAFYRERFRDLLEDG 126

  Fly   140 LLISNGHHWRHHRKMIAPTFHQSILKSFVPTFVDHS----------KAVVARMGLEAGKS-FDVH 193
            :..::...|:..|::.....|.|       .|::|:          |.|.....|...|. ||:.
plant   127 IFNADDELWKEERRVAKTEMHSS-------RFLEHTFTTMRDLVDQKLVPLMENLSTSKRVFDLQ 184

  Fly   194 DYMSQTTVDILLSTAMGV--KKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSI----YKFT 252
            |.:.:.|.|.:..:|.||  ..|..|.....:|:|..|..:          |.|...    :.:.
plant   185 DLLLRFTFDNICISAFGVYPGSLETGLPEIPFAKAFEDATE----------YTLARFLIPPFVWK 239

  Fly   253 KLREKG---DRMMN----IILGMTSKVVKDRKENFQEESRAIVEEISTPVASTPASKKEGLRDDL 310
            .:|..|   :|.:|    |:....:|.|::|:...                     :|.|..:|.
plant   240 PMRFLGIGYERKLNNAVRIVHAFANKTVRERRNKM---------------------RKLGNLNDY 283

  Fly   311 DDIDENDVGAKRRLALLDAMV--EMAKNPDIE----WNEKDIMDEVNTIMFEGHDTTSAGSSFAL 369
            .|             ||..::  |..|..|..    :::|...:...:.:..|.||||....:..
plant   284 AD-------------LLSRLMQREYEKEEDTTRGNYFSDKYFREFCTSFIIAGRDTTSVALVWFF 335

  Fly   370 CMMGIHKDIQAKVFAEQKAIFGDNMLRDCTFADT---------MEMKYLERVILETLRLYPPVPL 425
            .::..|.:::.::..|.:.|     .|..|..:|         .||.||:..:.|:|||||.||:
plant   336 WLVQKHPEVEKRILREIREI-----KRKLTTQETEDQFEAEDFREMVYLQAALTESLRLYPSVPM 395

  Fly   426 IARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDIYPNP-TKFDPDNFLPE-RMANRHYYSFI 488
            ..::...|..|..|. .|.||..:....|.:.|...|:... .:|.|:.::.| |:.:...:.::
plant   396 EMKQALEDDVLPDGT-RVKKGARIHYSVYSMGRIESIWGKDWEEFKPERWIKEGRIVSEDQFKYV 459

  Fly   489 PFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVHSTDTEADFKLQADIILKL------ENGFNVSL 547
            .|:.|||.|||:|:|..::|::.:.|:..|.|.....:       :|:.||      :||.||.|
plant   460 VFNGGPRLCVGKKFAYTQMKMVAAAILMRYSVKVVQGQ-------EIVPKLTTTLYMKNGMNVML 517

  Fly   548 EKRQY 552
            :.|.:
plant   518 QPRDW 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	p450	58..518	CDD:278495	112/518 (22%)
CYP86C1	NP_173862.1	p450	90..520	CDD:299894	110/493 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010