DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4g1 and CYP86C4

DIOPT Version :9

Sequence 1:	NP_525031.1	Gene:	Cyp4g1 / 30986	FlyBaseID:	FBgn0010019	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_172774.1	Gene:	CYP86C4 / 837873	AraportID:	AT1G13150	Length:	529	Species:	Arabidopsis thaliana

Alignment Length:	597	Identity:	129/597 - (21%)
Similarity:	236/597 - (39%)	Gaps:	158/597 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LGFSPMLTTLVGTLVAMALYEYWRRNSREYRMVANIPSPPELPILGQAHVAAGLSNAEILAVGLG 86
            |....:|.:|:|..|...|.|          .:.|...|...|:.|            |......
plant    11 LSLFDLLLSLLGLFVFCCLRE----------KLTNKRGPMLWPVFG------------ITLEFFF 53

  Fly    87 YLNK-YGETMKA-------------WL----GNVLLVFLTNPSDIELIL-SGHQHLTKAEEYRYF 132
            ::|. ||...::             ||    |.|..|    |:::|.:| :..::..|.   .:|
plant    54 HINDVYGWVTRSLKKCRGTFLYRGVWLDGSYGAVTCV----PANVEYMLKTNFKNFPKG---TFF 111

  Fly   133 KPWFGD----GLLISNGHHWRHHRKMIAPTFHQSILKSFVPTFVDHS----KAVVARMGLEAGKS 189
            |..|.|    |:..::...|:..|::|....|.:       .||:||    :.:|.:..|:..:|
plant   112 KSRFNDLLEEGIFNADDDSWKEQRRIIITEMHST-------GFVEHSFQTTQHLVRKKLLKVMES 169

  Fly   190 -------FDVHDYMSQTTVDILLSTAMGVK------KLPE--GNKSFEYAQAVVDMCDIIHKRQV 239
                   ||:.|...:.|.||:....:|..      .||:  ..|:||.|........:|.....
plant   170 FAKSQEAFDLQDVFLRLTFDIICLAGLGADPETLAVDLPQVPFAKAFEEATESTLFRFMIPPFIW 234

  Fly   240 KLLYRLDSIYKFTKLREKGDRM-MNIILGMTSKVVKDR----KENFQEESRAIVEEISTPVASTP 299
            |.:..||:.|      |||.|: :.::.|...|::.||    ||....::|:   ::.:.:....
plant   235 KPMRFLDTGY------EKGLRIAVGVVHGFVDKMIVDRICELKEEETLDNRS---DVLSRIIQIE 290

  Fly   300 ASKKEGLRDDLDDIDENDVGAKRRLALLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAG 364
            :.|:|      ::||.:.:...|:..                         .:.:..|.||:|..
plant   291 SHKRE------NEIDPSTIRFFRQFC-------------------------TSFILAGRDTSSVA 324

  Fly   365 SSFALCMMGIHKDIQAKVFAEQKAIF---GDNMLRD----CTFADTMEMKYLERVILETLRLYPP 422
            .|:...::..|.:::.|:..|.:.|.   ||:....    .|..:...|.||:..:.|||||:||
plant   325 LSWFCWVIQKHPEVENKIICEIREILRQRGDSPTSKNESLFTVKELNNMVYLQAALSETLRLFPP 389

  Fly   423 VPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDIYPNPTKFDPDNFLPER------MAN 481
            :|:..::...|..|..|.: |.||:.|....|.:.|...|:..    |.:.|.|||      ..:
plant   390 IPMEMKQAIEDDVLPDGTF-VRKGSRVYFSIYAMGRMESIWGK----DCEIFRPERWIQAGKFVS 449

  Fly   482 RHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVHSTDTEADFKLQADII--------LK 538
            ...:.::.|:||||.|:|:.:|.|::|::.::::..|.:         |:..|.:        |.
plant   450 DDQFKYVVFNAGPRLCIGKTFAYLQMKMIAASVLLRYSI---------KVVQDHVIAPRVTTNLY 505

  Fly   539 LENGFNVSLEKR 550
            ::.|..|::..|
plant   506 MKYGLKVTITPR 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	p450	58..518	CDD:278495	114/519 (22%)
CYP86C4	NP_172774.1	CYP86A	73..510	CDD:410687	111/504 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010