DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4g1 and LUT1

DIOPT Version :9

Sequence 1:	NP_525031.1	Gene:	Cyp4g1 / 30986	FlyBaseID:	FBgn0010019	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_190881.2	Gene:	LUT1 / 824479	AraportID:	AT3G53130	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	584	Identity:	133/584 - (22%)
Similarity:	246/584 - (42%)	Gaps:	113/584 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AVEVVQETLQQAASSSSTTVLGFSP-MLTTLVGTLVAMALYEYWRRNSREYRMVANIPSPPELPI 65
            ::|..:..|:..:|.|.:.|   || .||||..||.:       .:|......:||........:
plant    38 SIEKPKPKLETNSSKSQSWV---SPDWLTTLTRTLSS-------GKNDESGIPIANAKLDDVADL 92

  Fly    66 LGQAHVAAGLSNAEILAVGL-GYLNKYGETMKAWLGNVLLVFLTNPSDIELILSGHQHLTK---A 126
            ||.|           |.:.| .::|:||...:...|....|.:::|:..:.:|..:....|   |
plant    93 LGGA-----------LFLPLYKWMNEYGPIYRLAAGPRNFVIVSDPAIAKHVLRNYPKYAKGLVA 146

  Fly   127 EEYRYFKPWFGDGLLISNGHHWRHHRKMIAPTFHQSILKSFVP-TFVDHSKAVVARMG--LEAGK 188
            |...:.   ||.|..|:.|..|...|:.:.|:.|:..|...|. .|...::.:|.::.  .|.|.
plant   147 EVSEFL---FGSGFAIAEGPLWTARRRAVVPSLHRRYLSVIVERVFCKCAERLVEKLQPYAEDGS 208

  Fly   189 SFDVHDYMSQTTVDILLSTAMGVKKLPEGNKSFEY-----------AQAVVDMCDIIHKRQVKLL 242
            :.::....||.|:|::            |...|.|           .:||.........|...||
plant   209 AVNMEAKFSQMTLDVI------------GLSLFNYNFDSLTTDSPVIEAVYTALKEAELRSTDLL 261

  Fly   243 --YRLDSIYKFTKLREKGDRMMNIILGMTSKVVKDRKENFQEESRAIVEEISTPVASTPASKKEG 305
              :::|::.|....:.|.::.:.:|        ::..|:...:.:.|||             :||
plant   262 PYWKIDALCKIVPRQVKAEKAVTLI--------RETVEDLIAKCKEIVE-------------REG 305

  Fly   306 LR-DDLDDIDENDVGAKRRLALLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFAL 369
            .| :|.:.:::.|....|.|        :|...::  :...:.|::.:::..||:||.:..::.|
plant   306 ERINDEEYVNDADPSILRFL--------LASREEV--SSVQLRDDLLSMLVAGHETTGSVLTWTL 360

  Fly   370 CMMGIHKDIQAKVFAEQKAIFGDNML--RDCTFADTMEMKYLERVILETLRLYPPVPLIARRLDY 432
            .::.  |:..|...|:::.   |.:|  |:..|.|..|:||:.|.|.|::||||..|::.||...
plant   361 YLLS--KNSSALRKAQEEV---DRVLEGRNPAFEDIKELKYITRCINESMRLYPHPPVLIRRAQV 420

  Fly   433 DLKLASGPYTVPKGTTVIVLQYCVHRRPDIYPN-----PTKFDPDNFLPERMANRHYYSFIPFSA 492
            . .:..|.|.|..|..:::..|.:||..:::..     |.:||.|..:|..  ....:.|||||.
plant   421 P-DILPGNYKVNTGQDIMISVYNIHRSSEVWEKAEEFLPERFDIDGAIPNE--TNTDFKFIPFSG 482

  Fly   493 GPRSCVGRKYAMLKLKVLLSTIVRNYIVHSTDTEADFKLQADIILKLENGFNVSLEKRQYATVA 556
            |||.|||.::|:::..|.|:..::...|         :|..|..:.:..|..:......|..|:
plant   483 GPRKCVGDQFALMEAIVALAVFLQRLNV---------ELVPDQTISMTTGATIHTTNGLYMKVS 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	p450	58..518	CDD:278495	111/487 (23%)
LUT1	NP_190881.2	PLN02936	56..539	CDD:178524	129/566 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.110