DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4g1 and cyp2j20

DIOPT Version :9

Sequence 1:	NP_525031.1	Gene:	Cyp4g1 / 30986	FlyBaseID:	FBgn0010019	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	XP_001337781.3	Gene:	cyp2j20 / 797309	ZFINID:	ZDB-GENE-041210-324	Length:	496	Species:	Danio rerio

Alignment Length:	527	Identity:	124/527 - (23%)
Similarity:	200/527 - (37%)	Gaps:	134/527 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 PSPPELPILGQAH------VAAGLSNAEILAVGLGYLNKYGETMKAWLGNVLLVFLTNPSDIELI 116
            |.|..|||:|..|      :...||.         :..|||:.....|....:|          :
Zfish    39 PGPWSLPIIGDIHHIDPSKLHLQLSE---------FAEKYGKIFSLRLFGPRIV----------V 84

  Fly   117 LSGHQHLTKAEEY---------RYFKPWFGD-----GLLISNGHHWRHHRKMIAPTFHQSIL--K 165
            |:|: :|.| |.|         |...|.|.|     ||:.|:|:.|:..|:....|.....|  |
Zfish    85 LNGY-NLVK-EVYTQEGDNLADRAILPLFHDIIGDKGLVASSGYKWKQQRRFALSTLRNFGLGKK 147

  Fly   166 SFVPTFVDHSKAVVARMGLEAGKSFDVHDYMSQTTVDILLSTAMG--VKKLPEGNKSFEYAQAVV 228
            :..|:....|..:...:..|.|:.||..         :||:.|:.  :..|..||: |:|:.
Zfish   148 NLEPSINLESGFLNEAISNEQGQPFDPR---------LLLNNAVSNVICALVFGNR-FDYSD--- 199

  Fly   229 DMCDIIHKRQVKLLYRLDSIYKFTKLREKG--DRMMNI--------------ILGMTSKVVKDRK 277
                  ||.|..|....::::     .|.|  .::.|:              |:.:..|:::...
Zfish   200 ------HKFQTLLKNINETVH-----LEGGICAQLYNMLPWLMRLLPGPHKRIIALWGKLIEFVG 253

  Fly   278 ENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRLALLDAMVEMAKNPDIEWN 342
            |...|..          |...|.:.    ||.:|             ..||   ||.|:.|....
Zfish   254 EKVNEHK----------VDHDPLNP----RDYID-------------CFLD---EMEKHKDDTAA 288

  Fly   343 EKDI-------MDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNMLRDCTF 400
            ..|:       :|    :...|.:|||....:.|..|..:.:|||||..|...|.|.:  |..:.
Zfish   289 GFDVENLCICTLD----LFVAGTETTSTTLYWGLLYMMKYPEIQAKVQQEIDVIVGGS--RQPSV 347

  Fly   401 ADTMEMKYLERVILETLRLYPPVPL-IARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDIYP 464
            :|...|.|...||.|..|:...:|: :||....|.::..  |::||||.|......|......:.
Zfish   348 SDRDNMPYTNAVIHEIQRMGNIIPINLARTTSEDTQIEK--YSIPKGTMVTSNLTSVLFDESEWE 410

  Fly   465 NPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVH---STDTE 526
            .|..|:|.:||......|...:|:|||.|.|.|:|.:.|.::|.:..|::::.:...   ..:..
Zfish   411 TPHSFNPGHFLDAEGKFRRRDAFLPFSLGKRVCLGEQLARMELFLFFSSLLQRFTFSPPAGVEPS 475

  Fly   527 ADFKLQA 533
            .|:.|.|
Zfish   476 LDYNLGA 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	p450	58..518	CDD:278495	121/507 (24%)
cyp2j20	XP_001337781.3	p450	38..492	CDD:278495	124/527 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010