DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4g1 and Cyp4f37

DIOPT Version :9

Sequence 1:	NP_525031.1	Gene:	Cyp4g1 / 30986	FlyBaseID:	FBgn0010019	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	XP_038935973.1	Gene:	Cyp4f37 / 691312	RGDID:	1585102	Length:	526	Species:	Rattus norvegicus

Alignment Length:	502	Identity:	145/502 - (28%)
Similarity:	237/502 - (47%)	Gaps:	48/502 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 SPPELPILGQAHVAAGLSNAEILAVGLGYLNKYGETMK----AWLGNVLLVF-LTNPSDIELILS 118
            ||.....||  |:....||.|    |:..:.:.|:|.:    .|||.|..|. |.:|:.:..:|.
  Rat    54 SPKRNWFLG--HLGVIQSNEE----GMQLVTEMGQTFRDVHLIWLGPVSPVLRLVDPAFVAPLLQ 112

  Fly   119 GHQHLTKAEE--YRYFKPWFGDGLLISNGHHWRHHRKMIAPTFHQSILKSFVPTF-----VDHSK 176
            ....:...:.  ..:.|||.||||.:|:|..|..||:::.|.||..|||.:|.||     :.|:|
  Rat   113 APALVAPKDPTFLHFLKPWLGDGLFLSSGDKWSRHRRLLTPAFHFDILKPYVKTFNQSVNIMHAK 177

  Fly   177 AVVARMGLEAGKSFDVHDYMSQTTVDILLSTAMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKL 241
              ...:.||.....::.:.:|..|:|.|.....|.....:.:.| ||..|.:::..:..||..||
  Rat   178 --WKHLCLEGSARLEMFENISLMTLDSLQKCLFGFDSNCQESPS-EYISATLELSSLTRKRSYKL 239

  Fly   242 LYRLDSIYKFTKLREKGDRMMNIILGMTSKVVKDRKENFQEESRAIVEEISTPVASTPASKKEGL 306
            ...||.:|..|...::..:..:::...|..|:::|:.....:.   |:|..       .||.:..
  Rat   240 FLYLDFLYYRTADGQRFRKACDLVHSFTDAVIRERRRLLSSQG---VDEFL-------ESKTKSK 294

  Fly   307 RDDLDDIDENDVGAKRRLALLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCM 371
            ...||.||          .||.|..|..|    |.:::||..|.:|.||.|||||::..|:.|..
  Rat   295 SKTLDFID----------VLLLAKDEHGK----ELSDEDIRAEADTFMFGGHDTTASALSWILYN 345

  Fly   372 MGIHKDIQAKVFAEQKAIFGDNMLRDCTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKL 436
            :..|.:.|.:...|...:..|....:..:.|..::.:|...|.|:|||:||...:.||...|:.|
  Rat   346 LASHPEYQERCRQEVWELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPAVDLLRRCTQDIVL 410

  Fly   437 ASGPYTVPKGTTVIVLQYCVHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRK 501
            ..| ..:|||...::..:.:|..|.::|:|..:||..|.||....|...||||||||||:|:|:.
  Rat   411 PDG-RVIPKGNICVISIFGIHHNPSVWPDPEVYDPFRFDPENRQKRSPLSFIPFSAGPRNCIGQT 474

  Fly   502 YAMLKLKVLLSTIVRNYIVHSTDTEADFKLQADIILKLENGFNVSLE 548
            :||.::||.:...:..:.....|.|.  :.:.::||:.|.|..:.:|
  Rat   475 FAMNEVKVAVGLTLLRFRFLPDDKEP--RRKPELILRAEGGLWLRVE 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	p450	58..518	CDD:278495	138/470 (29%)
Cyp4f37	XP_038935973.1	CYP4F	74..517	CDD:410772	135/472 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920