Protein Alignment Cyp4g1 and Cyp3a57

DIOPT Version :10

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001093650.1
• Gene: Cyp3a57 / 622127
• MGIID: 3646373
• Length: 503
• Species: Mus musculus
• Alignment Length: 565
• Identity: 142/565 - (25%)
• Similarity: 237/565 - (41%)
• Gaps: 127/565 - (22%)

  Fly    31 LVGTLVAMALYEYWRRNSREYRMVANIPSPPELPILGQAHVAAGLSNAEILAVGLGYLN------ 89
            ||.:||...:|..:   |........||.|..||:.|..               :.||:
Mouse    15 LVTSLVFFYIYGTY---SHGLFKKLGIPGPKPLPLFGNI---------------INYLDGMWKFD 61

  Fly    90 -----KYGETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYF---KPWFGDGLL----- 141
                 |||:....:.|...::.:.:|..|:::|       ..|.|..|   :|:...|.|
Mouse    62 DDCYKKYGKIWGFYEGPQPILAIMDPEIIKIVL-------VKECYSVFTNRRPFGPVGFLKKSIT 119

  Fly   142 ISNGHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLEAGKS--FDVHDYMSQTTVDIL 204
            ||....|:..|.:::|||..|.||...|....:...:|..:..|..|.  .::.|.....::|::
Mouse   120 ISEDEEWKRLRTLLSPTFTSSKLKEMFPIMRQYGDILVRNLRREEEKEEPINMKDIFGAYSMDVI 184

  Fly   205 LSTAMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVK------------LLYRLDSIYKFTKLREK 257
            ..|:.||......|....:.|.:        |:.:|            |...|..||:...|...
Mouse   185 TGTSCGVNIDSLNNPQDPFVQKI--------KKILKFKFFDPFLLSVVLFPFLTPIYEMLNLSIF 241

  Fly   258 GDRMMNIILGMTSKVVKDRKENFQEESRAIVEEISTPVASTPASK-KEGLRDDLDDIDENDVGAK 321
            ..:.||.......|:.|||.: :.:::|....::   :.:|..|| :|.|:
Mouse   242 PRQSMNFFKKFVKKMKKDRLD-YNQKNRVDFLQL---MMNTQNSKGQESLK-------------- 288

  Fly   322 RRLALLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQ 386
               ||.|  :|||....|             .:|.|:|.||...||.:..:..|.|:|.|:   |
Mouse   289 ---ALSD--LEMAAQTLI-------------FIFGGYDGTSTSISFIMYELATHPDVQKKL---Q 332

  Fly   387 KAIFGDNMLRD---CTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTT 448
            ..|  |..|.:   .|:...|:|:||:.|:.|:|||||.|..|.|....|::: .|.: :||||.
Mouse   333 DEI--DRALPNKAPVTYDALMDMEYLDMVVNESLRLYPVVSRIDRFSKKDVEI-HGVF-IPKGTI 393

  Fly   449 VIVLQYCVHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLST 513
            |::..|.:||.|:.:|.|..|.|:.|..|...|...|.::||..|||:|:|.::|::.:|:.::.
Mouse   394 VMIPIYPLHRDPEYWPEPEDFCPERFSKENKGNIDPYIYMPFGNGPRNCIGMRFALISVKLAVTG 458

  Fly   514 IVRNYIVHSTD---------TEADFKLQADIILKLENGFNVSLEK 549
            :::|:.|...:         .:..|:.:..||||.     ||.:|
Mouse   459 VLQNFTVQPCEETQIPVKISRQPIFRPEKPIILKF-----VSRDK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	123/487 (25%)
Cyp3a57	NP_001093650.1	cytochrome_P450	67..492	CDD:477761	123/482 (26%)