Protein Alignment Cyp4g1 and Cyp3a25

DIOPT Version :10

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_062766.2
• Gene: Cyp3a25 / 56388
• MGIID: 1930638
• Length: 503
• Species: Mus musculus
• Alignment Length: 569
• Identity: 135/569 - (23%)
• Similarity: 239/569 - (42%)
• Gaps: 126/569 - (22%)

  Fly    28 LTTLVGTLVAMALYEYWRRNSREYRMVANIPSPPELPILGQAHVAAGLSNAEILAVGLGYLN--- 89
            :.|.|..:.::.|:..:...|........||.|..||:||..               ..|.:
Mouse     9 IETWVLLVTSLVLFYIYGTYSHGLFKKLGIPGPKPLPLLGTI---------------FNYYDGMW 58

  Fly    90 --------KYGETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKP--WFGDGLLISN 144
                    |||:....:.|...::.:.:|..|:::|....:...... |:|.|  :....:.||.
Mouse    59 KFDEDCYKKYGKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNR-RFFGPVGFMKKAITISE 122

  Fly   145 GHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKAVV--ARMGLEAGKSFDVHDYMSQTTVDILLST 207
            ...|:..|.:::|||....||...|....:...:|  .|...|.|:...:.|.....::|::..|
Mouse   123 DEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPISMKDIFGAYSMDVITGT 187

  Fly   208 AMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYKF----------------TKLRE 256
            :.||.                  .|.::..|...:.:...|.||                |.:.|
Mouse   188 SFGVN------------------VDSLNNPQDPFVQKAKKILKFKIFDPFLLSIILFPFLTPIYE 234

  Fly   257 KGDRMMNIILGMTSKVVKDRKENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAK 321
                |:|.     |...:|....|::..:.:.:|   .:||...::.:.|:..::  .:|..|.:
Mouse   235 ----MLNF-----SIFPRDSMNFFKKFVKRMKKE---RLASNQKNRVDFLQLMMN--TQNSKGQE 285

  Fly   322 RRLALLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQ 386
            .:.||.|  :|||....|             .:|.|:|.||...|..:..:..|.|:|.|:   |
Mouse   286 SQKALSD--LEMAAQAVI-------------FIFGGYDATSTSISLIMYELATHPDVQKKL---Q 332

  Fly   387 KAIFGDNMLRD---CTFADTMEMKYLERVILETLRLYPPVPLIARRLD----YDLKLASGPYTVP 444
            ..|  |..|.:   .|:...|:|:||:.|:.|:|||||    ||.||:    .|::: :|.: :|
Mouse   333 DEI--DRTLPNKAPVTYDALMDMEYLDMVVNESLRLYP----IAIRLERVSKKDVEI-NGVF-IP 389

  Fly   445 KGTTVIVLQYCVHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKV 509
            |||.|::..|.:||.|:.:|.|.:|.|:.|..|...|...|.::||..|||:|:|.::|::.:|:
Mouse   390 KGTVVMIPIYPLHRNPEYWPEPQEFCPERFSKENKGNIDPYIYMPFGNGPRNCIGMRFALISIKL 454

  Fly   510 LLSTIVRNYIVHSTD---------TEADFKLQADIILKLENGFNVSLEK 549
            .:..:::|:.|...:         .|..|:.:..||||:     ||.:|
Mouse   455 AVIGVLQNFTVQPCEETQIPLKISREPIFQPEKPIILKV-----VSRDK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	118/488 (24%)
Cyp3a25	NP_062766.2	CYP3A	67..492	CDD:410743	118/483 (24%)