Protein Alignment Cyp4g1 and Cyp3a41a

DIOPT Version :10

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_059092.2
• Gene: Cyp3a41a / 53973
• MGIID: 1858451
• Length: 504
• Species: Mus musculus
• Alignment Length: 542
• Identity: 147/542 - (27%)
• Similarity: 241/542 - (44%)
• Gaps: 95/542 - (17%)

  Fly    29 TTLVGTLVAMALYEYWRRNSREYRMVANIPSPPELPILGQA-HVAAGLSNAEILAVGLGYLNKYG 92
            |.::..::.:.||.|..|....::. ..||.|..||.||.. :...||...:     :....|||
Mouse    11 TWVLLAIILVLLYRYGTRTHGLFKK-QGIPGPKPLPFLGTVLNYYKGLWKFD-----MECYEKYG 69

  Fly    93 ETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKP--WFGDGLLISNGHHWRHHRKMI 155
            :|...:.|.:.|..:|:|..|:.:|. .:..:.....|.|.|  .....:.||....|:.:|.::
Mouse    70 KTWGLFDGQMPLFVITDPEMIKNVLV-KECFSVFTNRREFGPVGIMSKAISISKDEEWKRYRALL 133

  Fly   156 APTFHQSILKSFVPTFVDHSKAVVARMGLEA--GKSFDVHDYMSQTTVDILLSTAMGVK----KL 214
            :|||....||...|....:...:|..:..||  ||...:.|.:...::|::.||:.||.    ..
Mouse   134 SPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYSIDVITSTSFGVNVDSLNN 198

  Fly   215 PEGNKSFEYAQAV--VDMCDIIHKRQVKLLYRLDSIYKFTKLREKGDRMMNIILGMTSKVVKDRK 277
            || :...|.|:.:  ||..|.: ...|.|...|..:|:          |:||.:     ..||..
Mouse   199 PE-DPFVEKAKGILRVDFFDPL-VFSVVLFPFLTPVYE----------MLNICM-----FPKDSI 246

  Fly   278 ENFQ------EESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRLALLDAMVEMAKN 336
            |.|:      :|||.                              |...|.|:..|..|:....|
Mouse   247 EFFKKFVNRMKESRL------------------------------DSKQKHRVDFLQLMMNAHNN 281

  Fly   337 PDIEWNEKDIMD-EVN----TIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNMLR 396
            ...:.:.|.:.| |:.    ..:|.|::|||:..||.|..:..|.|||.|:   |:.|  |..|.
Mouse   282 SKDKDSHKALSDMEITAQSIVFIFAGYETTSSTLSFTLYCLATHPDIQKKL---QEEI--DETLP 341

  Fly   397 D---CTFADTMEMKYLERVILETLRLYPPVPLIARRLD----YDLKLASGPYTVPKGTTVIVLQY 454
            :   .|:...|||:||:.|:.|||||||    |..||:    .|::| :|.| :|||:||::..|
Mouse   342 NKAPPTYDTVMEMEYLDMVLNETLRLYP----IGNRLERFCKKDVEL-NGVY-IPKGSTVMIPSY 400

  Fly   455 CVHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYI 519
            .:|..|..:|.|.:|.|:.|..|...:...|.::||..|||:|:|.::|.:.:|:.|:.:::|:.
Mouse   401 ALHHDPQHWPEPEEFQPERFSKENKGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFS 465

  Fly   520 VH-STDTEADFKLQADIILKLE 540
            .. ..:|:...||....:|:.|
Mouse   466 FQPCQETQIPLKLSRQGLLQPE 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	131/478 (27%)
Cyp3a41a	NP_059092.2	CYP3A	67..493	CDD:410743	133/480 (28%)