DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4g1 and Cyp313a1

DIOPT Version :9

Sequence 1:	NP_525031.1	Gene:	Cyp4g1 / 30986	FlyBaseID:	FBgn0010019	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_650368.1	Gene:	Cyp313a1 / 41759	FlyBaseID:	FBgn0038236	Length:	492	Species:	Drosophila melanogaster

Alignment Length:	542	Identity:	157/542 - (28%)
Similarity:	250/542 - (46%)	Gaps:	69/542 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 MLTTLVGTLVAMA----LYEYWRRNSREYRMVANIPSPPELPILGQAHVAAGLSN----AEILAV 83
            |||  :..|:|:.    :|..|.|. |.|.::..||.|..|||||     :.|.|    ...|:.
  Fly     1 MLT--INLLLAVGALFWIYFLWSRR-RLYFLMLKIPGPIGLPILG-----SSLENIITYKRKLSF 57

  Fly    84 GLGYLNKYGETMKAWLGNVLLVFLTNPSDIELILSG------HQHLTKAEEYRYFKPWFGDGLLI 142
            ...||||||.|:..|:|.|..:...:|..:|.|.|.      .||:..|     .....|:|||.
  Fly    58 RTKYLNKYGSTILTWMGPVPFIVTRDPKVVEDIFSSPDCHNKSQHIVNA-----ITSCMGNGLLG 117

  Fly   143 SNGHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLEAGK-SFDVHDYMSQTTVDILLS 206
            ....||...||...|:|.|.:|.||...|...:|.::..:.....| ..||...|.:.:..|...
  Fly   118 KQDPHWLDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKGEIDVVPEMLRWSFKIAAQ 182

  Fly   207 TAMG--VKKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYKFTKLREKGDRMMNIILGMT 269
            |.||  ||.    ::.|:....|.....:|....:.:|..|..           :||::.|.|..
  Fly   183 TTMGSEVKH----DEHFKNGSLVESFESLISHSTLNILMPLVQ-----------NRMISKICGYD 232

  Fly   270 SKVVKDRKENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRLALLDAMVEMA 334
                |.|.:||....:.:...::..|...|.:         |...|:::       :::..:|:.
  Fly   233 ----KLRADNFSRIQKMLDNVVNKKVNPLPKT---------DSDPESNI-------VINRAMELY 277

  Fly   335 KNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNMLRDCT 399
            :..||.:  .|:..|...::..|:||::.....||.::..|.:.|..||.|...:|.|......|
  Fly   278 RKGDITY--MDVKSECCIMIAAGYDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGIT 340

  Fly   400 FADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDIY- 463
            :.|..::.||||||.|||||.|.:|:.||....|::|::| ..:|||..:.:..:..||.|:::
  Fly   341 YPDMQKLDYLERVIKETLRLIPAIPITARETKNDVRLSNG-VLIPKGVVIGIDMFHTHRNPEVWG 404

  Fly   464 PNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVHSTDTEAD 528
            |:...|:|||||.|.|..:|.|::|||:.|.|:|:|.||||:..|..|..|:|||.:.::....|
  Fly   405 PDADNFNPDNFLAENMEQKHPYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKISTSTLYKD 469

  Fly   529 FKLQADIILKLENGFNVSLEKR 550
            .....::.:||.....:.|::|
  Fly   470 LVYVDNMTMKLAEYPRLKLQRR 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	p450	58..518	CDD:278495	139/473 (29%)
Cyp313a1	NP_650368.1	p450	33..463	CDD:299894	141/477 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	4	3.960