DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4g1 and Cyp313a5

DIOPT Version :9

Sequence 1:	NP_525031.1	Gene:	Cyp4g1 / 30986	FlyBaseID:	FBgn0010019	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_650168.1	Gene:	Cyp313a5 / 41486	FlyBaseID:	FBgn0038005	Length:	487	Species:	Drosophila melanogaster

Alignment Length:	544	Identity:	143/544 - (26%)
Similarity:	245/544 - (45%)	Gaps:	78/544 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 MLTTLV--GTLVAMALYEYWRRNSREYRMVANIPSPPELPILGQAHVAAGLSNAEILAVGLGYLN 89
            |||..:  ...:.:.:|..|.|. |.|.|:..:|.|...|.:|.|.....|.....|...|  ..
  Fly     1 MLTLQIFEAFAIILCVYFLWSRR-RFYIMMLKLPGPMGFPFIGLAFEYIRLKRKIRLRTIL--FK 62

  Fly    90 KYGETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEY-RYFKPWFGDGLLISNGHHWRHHRK 153
            .||:|:..|:|...::....|..:|.|.:......::... :......|.|||....:||...||
  Fly    63 IYGKTVLTWIGLTPVLVTCEPKILEDIFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHWNERRK 127

  Fly   154 MIAPTFHQSILKSFVPTFVDHSKAVVARMG--LEAGKSFDVHDYMSQTTVDILLSTAMGVKKLPE 216
            ::.|:|..:.:.||||...:.:..:|..:.  ::.|              ||.|        |||
  Fly   128 LLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGG--------------DINL--------LPE 170

  Fly   217 GNK-SFEYAQAVVDMCDIIHKRQVKLLYRLDSIYKFTKLREKGDRMMNII-------------LG 267
            .|| ||:.| |.:.|.|.:         |..:.|:...|.|....:.|:|             ||
  Fly   171 LNKWSFKIA-AQITMGDEV---------RNQANYQNGNLLESYKALNNLIPIGVVMPWLRNKYLG 225

  Fly   268 MTSKVVKDRKENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRLALLDAMVE 332
            ......|.|.|...:.:..|.:.|...::||..|.:.                    ||:|.::.
  Fly   226 KLFSYEKRRLEAATQSNAFIKDIIDKKLSSTDNSSEP--------------------ALIDRILN 270

  Fly   333 MAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNMLRD 397
            :.:..::.::  |:|.|.:.|:|...||.|...:..|.:|.:....|..||.|...:|......:
  Fly   271 LVRIGELSYD--DVMGEFSNIIFAASDTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFE 333

  Fly   398 CTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDI 462
            .:.||..::..|:||:.||:||.|.|||:.|:..:.::|::|.| :|:|.|:::..:..||..||
  Fly   334 ASHADLEKLVKLDRVLHETMRLIPAVPLLIRQTSHSIQLSNGFY-IPEGVTLMIDIFHTHRNKDI 397

  Fly   463 Y-PNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVHSTDTE 526
            : |....|:|||||||....|..||::|||.|.::|:|.|.:::..|:.|:.|:|||::.:|...
  Fly   398 WGPQANAFNPDNFLPENKRARPPYSYLPFSKGKKTCLGWKLSLISAKLALAKILRNYMLSTTFLY 462

  Fly   527 ADFKLQADIILKLENGFNVSLEKR 550
            .|.:...:..:||.....:::::|
  Fly   463 KDLRFIDNTTMKLAEQPLLAVKRR 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	p450	58..518	CDD:278495	127/477 (27%)
Cyp313a5	NP_650168.1	p450	33..458	CDD:299894	129/481 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960