Protein Alignment Cyp4g1 and Cyp3a44

DIOPT Version :10

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_796354.1
• Gene: Cyp3a44 / 337924
• MGIID: 2449818
• Length: 504
• Species: Mus musculus
• Alignment Length: 539
• Identity: 146/539 - (27%)
• Similarity: 238/539 - (44%)
• Gaps: 77/539 - (14%)

  Fly    24 FSPM-LTTLVGTLVAMALYEYWRRNSREYRMV--ANIPSPPELPILGQA-HVAAGLSNAEILAVG 84
            ||.: |.|||  |:|:.|...:|..:|.:.:.  ..||.|..||.||.. :...|     |....
Mouse     4 FSALSLDTLV--LLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYYTG-----IWKFD 61

  Fly    85 LGYLNKYGETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKP--WFGDGLLISNGHH 147
            :....|||:|...:.|...|:.:|:|..|:.:|. ...|:.....|.|.|  .....:.||....
Mouse    62 MECYEKYGKTWGLFDGQTPLLVITDPETIKNVLV-KDCLSVFTNRREFGPVGIMSKAISISKDEE 125

  Fly   148 WRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLEAGKSFDV--HDYMSQTTVDILLSTAMG 210
            |:.:|.:::|||....||...|....:...:|..:..||.|...|  .|.:...::|::.||:.|
Mouse   126 WKRYRALLSPTFTSGRLKEMFPVIEQYGDILVKYLRQEAEKGMPVAMKDVLGAYSMDVITSTSFG 190

  Fly   211 VKKLPEGNKSFEYAQAV-----VDMCDIIHKRQVKLLYRLDSIYKFTKLREKGDRMMNIILGMTS 270
            |......|....:.:..     ||..|       .||:.:......|.:.|    |:||.:
Mouse   191 VNVDSLNNPEDPFVEEAKKFLRVDFFD-------PLLFSVVLFPLLTPVYE----MLNICM---- 240

  Fly   271 KVVKDRKENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDEN--DVGAKRRLALLDAMVEM 333
                                       .|....|..:..:|.:.|:  |...|.|:..|..|:..
Mouse   241 ---------------------------FPNDSIEFFKKFVDRMQESRLDSNQKHRVDFLQLMMNS 278

  Fly   334 AKNPDIEWNEKDIMD---EVNTIMF--EGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDN 393
            ..|...:.:.|...:   .|.:|:|  .|::|||:..||.|..:..|.|||.|:.||......:.
Mouse   279 HNNSKDKDSHKAFSNMEITVQSIIFISAGYETTSSTLSFTLYCLATHPDIQKKLQAEIDKALPNK 343

  Fly   394 MLRDCTFADT-MEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVH 457
            ....|   || |||:||:.|:.|||||||.|..:.|....|::| :|.| :|||:.|::..|.:|
Mouse   344 ATPTC---DTVMEMEYLDMVLNETLRLYPIVTRLERVCKKDVEL-NGVY-IPKGSMVMIPSYALH 403

  Fly   458 RRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVH- 521
            ..|..:|:|.:|.|:.|..|...:...|.::||..|||:|:|.::|::.:|:.::.:::|:...
Mouse   404 HDPQHWPDPEEFQPERFSKENKGSIDPYVYLPFGIGPRNCIGMRFALMNMKLAVTKVLQNFSFQP 468

  Fly   522 STDTEADFKLQADIILKLE 540
            ..:|:...||....||:.|
Mouse   469 CQETQIPLKLSRQGILQPE 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	124/467 (27%)
Cyp3a44	NP_796354.1	CYP3A	67..493	CDD:410743	126/469 (27%)