DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4g1 and Cyp4f5

DIOPT Version :9

Sequence 1:	NP_525031.1	Gene:	Cyp4g1 / 30986	FlyBaseID:	FBgn0010019	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_775147.1	Gene:	Cyp4f5 / 286905	RGDID:	708364	Length:	526	Species:	Rattus norvegicus

Alignment Length:	502	Identity:	146/502 - (29%)
Similarity:	239/502 - (47%)	Gaps:	48/502 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 SPPELPILGQAHVAAGLSNAEILAVGLGYLNKYGETMK----AWLGNVLLVF-LTNPSDIELILS 118
            ||.....||  |:....||.|    |:..:.:.|:|.:    .|||.|:.|. |.:|:.:..:|.
  Rat    54 SPKRNWFLG--HLGTIQSNEE----GMRLVTEMGQTFRDIHLCWLGPVIPVLRLVDPAFVAPLLQ 112

  Fly   119 GHQHLTKAEE--YRYFKPWFGDGLLISNGHHWRHHRKMIAPTFHQSILKSFVPTF-----VDHSK 176
            ....:...:.  .|:.|||.||||.:|:|..|..||:::.|.||..|||.:|..|     :.|:|
  Rat   113 APALVAPKDTTFLRFLKPWLGDGLFLSSGDKWSRHRRLLTPAFHFDILKPYVKIFNQSVNIMHAK 177

  Fly   177 AVVARMGLEAGKSFDVHDYMSQTTVDILLSTAMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKL 241
              ...:.||.....::.:.:|..|:|.|.....|.....:.:.| ||..|::::..:|.||..:|
  Rat   178 --WKHLCLEGSARLEMFENISLMTLDSLQKCLFGFDSNCQESPS-EYISAILELSSLIIKRSQQL 239

  Fly   242 LYRLDSIYKFTKLREKGDRMMNIILGMTSKVVKDRKENFQEESRAIVEEISTPVASTPASKKEGL 306
            ...||.:|..|....:..:..:::...|..|:::|:.....:......|          ||.:..
  Rat   240 FLYLDFLYYRTADGRRFRKACDLVHNFTDAVIRERRRLLSSQGTDEFLE----------SKTKSK 294

  Fly   307 RDDLDDIDENDVGAKRRLALLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCM 371
            ...||.||          .||.|..|..|    |.:::||..|.:|.||.|||||::..|:.|..
  Rat   295 SKTLDFID----------VLLLAKDEHGK----ELSDEDIRAEADTFMFGGHDTTASALSWILYN 345

  Fly   372 MGIHKDIQAKVFAEQKAIFGDNMLRDCTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKL 436
            :..|.:.|.:...|...:..|....:..:.|..::.:|...|.|:|||:||...:.||...|:.|
  Rat   346 LARHPEYQERCRQEVWELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPAIDLLRRCTQDIVL 410

  Fly   437 ASGPYTVPKGTTVIVLQYCVHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRK 501
            ..| ..:|||...::..:.:|..|.::|:|..|||..|..|....|...||||||||||:|:|:.
  Rat   411 PDG-RVIPKGNICVISIFGIHHNPSVWPDPEVFDPFRFDSENRQKRSPLSFIPFSAGPRNCIGQT 474

  Fly   502 YAMLKLKVLLSTIVRNYIVHSTDTEADFKLQADIILKLENGFNVSLE 548
            :||.::||:::..:..:.|...|.|.  :.:.:|||:.|.|..:.:|
  Rat   475 FAMNEMKVVVALTLLRFRVLPDDKEP--RRKPEIILRAEGGLWLRME 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	p450	58..518	CDD:278495	137/470 (29%)
Cyp4f5	NP_775147.1	p450	52..516	CDD:278495	145/497 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D249473at33208
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920