Protein Alignment Cyp4g1 and Cyp3a23-3a1

DIOPT Version :10

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 551
• Identity: 137/551 - (24%)
• Similarity: 235/551 - (42%)
• Gaps: 109/551 - (19%)

  Fly    29 TTLVGTLVAMALYEYWRRNSREYRMVANIPSPPELPILGQA-HVAAGLSNAEILAVGLGYLNKYG 92
            |.::..:|.:.||.:..|....::. ..||.|..||..|.. :...||...::..     ..|||
  Rat    11 TWVLLAVVLVLLYGFGTRTHGLFKK-QGIPGPKPLPFFGTVLNYYMGLWKFDVEC-----HKKYG 69

  Fly    93 ETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKP--WFGDGLLISNGHHWRHHRKMI 155
            :....:.|.:.|..:|:...|:.:|. .:..:.....|.|.|  ..|..:.:|....|:.:|.::
  Rat    70 KIWGLFDGQMPLFAITDTEMIKNVLV-KECFSVFTNRRDFGPVGIMGKAISVSKDEEWKRYRALL 133

  Fly   156 APTFHQSILKSFVPTFVDHSKAVVARMGLEAGKSFDVHDYMSQTTVDILLSTAMGVKKLPEGNKS 220
            :|||....||...|....:...:|..:..|.||...|.:.....::|::.||:.||......|..
  Rat   134 SPTFTSGRLKEMFPVIEQYGDILVKYLRQEKGKPVPVKEVFGAYSMDVITSTSFGVNVDSLNNPK 198

  Fly   221 FEYAQAVVDMCDIIHKRQVKLLYRLD-------SIYKF---TKLREKGDRMMNIILGMTSKVVKD 275
            ..:.:            :.|.|.|:|       |:..|   |.:.|    |:||.:     ..||
  Rat   199 DPFVE------------KAKKLLRIDFFDPLFLSVVLFPFLTPVYE----MLNICM-----FPKD 242

  Fly   276 RKENFQ------EESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRLALLDAMV--- 331
            ..|.|:      :|:|                        ||.:.      |.|:..|..|:
  Rat   243 SIEFFKKFVYRMKETR------------------------LDSVQ------KHRVDFLQLMMNAH 277

  Fly   332 --EMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNM 394
              ...|......::.:|..:....:|.|::.||:..||.|..:..|.|.|.|:   |:.|  |..
  Rat   278 NDSKDKESHTALSDMEITAQSIIFIFAGYEPTSSTLSFVLHSLATHPDTQKKL---QEEI--DRA 337

  Fly   395 LRD---CTFADTMEMKYLERVILETLRLYPPVPLIARRLD----YDLKLASGPYTVPKGTTVIVL 452
            |.:   .|:...|||:||:.|:.|||||||    |..||:    .|::: :|.: :|||:.|::.
  Rat   338 LPNKAPPTYDTVMEMEYLDMVLNETLRLYP----IGNRLERVCKKDVEI-NGVF-MPKGSVVMIP 396

  Fly   453 QYCVHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRN 517
            .|.:||.|..:|.|.:|.|:.|..|...:...|.::||..|||:|:|.::|::.:|:.|:.:::|
  Rat   397 SYALHRDPQHWPEPEEFRPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQN 461

  Fly   518 YIVH-STDTEADFKLQAD--------IILKL 539
            :... ..:|:...||...        ||||:
  Rat   462 FSFQPCKETQIPLKLSRQGLLQPTKPIILKV 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	122/487 (25%)
Cyp3a23-3a1	NP_037237.2	CYP3A	67..491	CDD:410743	122/486 (25%)