Protein Alignment Cyp4g1 and Cyp3a18

DIOPT Version :10

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_665725.2
• Gene: Cyp3a18 / 252931
• RGDID: 628709
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 558
• Identity: 135/558 - (24%)
• Similarity: 231/558 - (41%)
• Gaps: 113/558 - (20%)

  Fly    26 PMLTTLVGTLVA---MALYEYWRRNSREYRMVANIPSPPELPILGQAHVAAGLSNAEILAVGLGY 87
            |.|:.....|:|   |..|.|...:...::.: .||.|..:|:.|           .|...|.|.
  Rat     5 PNLSIETWVLLATSLMLFYIYGTYSHGLFKKL-GIPGPKPVPLFG-----------TIFNYGDGM 57

  Fly    88 -------LNKYGETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYF--KPWFG------ 137
                   ..|||:....:.|....:.:.:|..|:::|       ..|.|..|  :..||
  Rat    58 WKFDDDCYKKYGKIWGFYEGPQPFLAIMDPEIIKMVL-------VKECYSVFTNRRCFGPMGFMK 115

  Fly   138 DGLLISNGHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLE--AGKSFDVHDYMSQTT 200
            ..:.:|....|:..|.:::|||....||...|....:...::..:..|  .|:..::.|.....:
  Rat   116 KAITMSEDEEWKRLRTILSPTFTSGKLKEMFPLMRQYGDTLLKNLRREEAKGEPINMKDIFGAYS 180

  Fly   201 VDILLSTAMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQ--------VKLLYRLDSIYKFTKLREK 257
            :|::..|:.||......|....:.|....    |.|.|        |.|...|..||:.......
  Rat   181 MDVITGTSFGVNVDSLNNPQDPFVQKAKK----ILKFQIFDPFLLSVVLFPFLTPIYEMLNFSIF 241

  Fly   258 GDRMMNIILGMTSKVVKDRKENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKR 322
            ..:.||..    .|.||..|:|..:.::....:....:.:|                :|..|.:.
  Rat   242 PRQSMNFF----KKFVKTMKKNRLDSNQKSRVDFLQLMMNT----------------QNSKGQES 286

  Fly   323 RLALLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQK 387
            :.||.|  :|||....|             .:|.|:|.||...||.:..:....::|.|:   |.
  Rat   287 QKALSD--LEMAAQAII-------------FIFGGYDATSTSISFIMYELATRPNVQKKL---QN 333

  Fly   388 AIFGDNMLRD---CTFADTMEMKYLERVILETLRLYPPVPLIARRLD----YDLKLASGPYTVPK 445
            .|  |..|.:   .|:...|||:||:.|:.|:|||||    ||.|||    .|::: :|.: :||
  Rat   334 EI--DRALPNKAPVTYDALMEMEYLDMVVNESLRLYP----IATRLDRVSKKDVEI-NGVF-IPK 390

  Fly   446 GTTVIVLQYCVHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVL 510
            ||.|.:..|.:||.|:.:..|.:|:|:.|..|...:...|.::||..|||:|:|.::|::.:|:.
  Rat   391 GTVVTIPIYPLHRNPEYWLEPEEFNPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALISMKLA 455

  Fly   511 LSTIVRNYIVHSTD-TEADFKL--------QADIILKL 539
            :..:::|:.:...: |:...|:        :..|||||
  Rat   456 VIGVLQNFNIQPCEKTQIPLKISRQPIFQPEGPIILKL 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	118/482 (24%)
Cyp3a18	NP_665725.2	CYP3A	67..492	CDD:410743	117/481 (24%)