Protein Alignment Cyp4g1 and cyp-25A1

DIOPT Version :10

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 536
• Identity: 121/536 - (22%)
• Similarity: 221/536 - (41%)
• Gaps: 96/536 - (17%)

  Fly    27 MLTTLVGTLVAMALYEYWRRNSR-EYRMVANIPSPPELPILGQAHVAAGLSNAEILAVGLGY--- 87
            :|::||.::....:|....|..| :.|....:..|.....||.....|.....      |||
 Worm     5 ILSSLVISIFTFFIYIILARRERFKLREKIGLSGPEPHWFLGNLKQTAERKEK------LGYDDA 63

  Fly    88 -------LNKYGETMKAWLGNVLLVFLTNPSDI-ELILSGHQHLTKAEEYRYFKPWFGDGLLISN 144
                   ..:||||...:.|:.:.:.::|..|| |:.:....:.:.......::.......|:.|
 Worm    64 NRWFNELHEQYGETFGIYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIYEANQLTASLLMN 128

  Fly   145 GHH--WRHHRKMIAPTFH-------QSILKSFVPTFVDHSKAVVARMGLEAGKSFDVHDYMSQTT 200
            .:.  |:|.|..|||.|.       |..:.|.|..|:|     :.|....:|:.:|::|.....|
 Worm   129 SYSSGWKHTRSAIAPIFSTGKMKAMQETINSKVDLFLD-----ILREKASSGQKWDIYDDFQGLT 188

  Fly   201 VDILLSTAMGVKKLPEGNKS---FEYAQAVVDMCDIIHKRQVK---LLYRLD----SIYKFTKLR 255
            :|::...|..:....:.:::   :..|:..:...||.|.:.:.   ||..|.    ::||:|.|
 Worm   189 LDVIGKCAFAIDSNCQRDRNDVFYVNAKKYISNIDIRHSKIIAASVLLPELSTFWKALYKYTPL- 252

  Fly   256 EKGDRMMNIILGMTSKVVKDRKENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGA 320
              .|..:.::.|::         |..|..|.                .||    .|.:|
 Worm   253 --ADAEIPLVEGLS---------NVYERRRG----------------GEG----SDSVD------ 280

  Fly   321 KRRLALLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAE 385
                 ||..::....:......::::::.....:..|::|||...::...::..:.::|.|::.|
 Worm   281 -----LLKLLLNREDDKSKPMTKQEVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEE 340

  Fly   386 QKAIFGDNMLRDCTFADTMEMKYLERVILETLRLYPPVPLIARRL-DYDLKLASGPYTVPKGTTV 449
               |.........|:.....||||:.|..||||.||||....||| ..|:.:....|  |||..|
 Worm   341 ---IMEAKENGGLTYDSIHNMKYLDCVYKETLRFYPPVIHFIRRLCREDITIRGQFY--PKGAIV 400

  Fly   450 IVLQYCVHRRPDIYPNPTKFDPDNF--LPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLS 512
            :.|.:.|||.|:.:.:|.:|.|:.|  ..|:.::   ..:|||..|||.|||.::|.::.|..:.
 Worm   401 VCLPHTVHRNPENWDSPEEFHPERFENWEEKSSS---LKWIPFGVGPRYCVGMRFAEMEFKTTIV 462

  Fly   513 TIVRNYIVHSTDTEAD 528
            .::..:.:...:.|||
 Worm   463 KLLDTFELKQFEGEAD 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	106/460 (23%)
cyp-25A1	NP_497775.3	CYP3A-like	73..495	CDD:410678	107/462 (23%)