Protein Alignment Cyp4g1 and Cyp3a9

DIOPT Version :10

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_671739.2
• Gene: Cyp3a9 / 171352
• RGDID: 708392
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 550
• Identity: 137/550 - (24%)
• Similarity: 242/550 - (44%)
• Gaps: 108/550 - (19%)

  Fly    27 MLTTLVGTLVAMALYEYWRRNSREYRMVANIPSPPELPILGQAHVAAGLSNAEILAVGLGYL--- 88
            |.|.|:..:..:.||.|...:...::.: .||.|..||.||           .|||...|:.
  Rat     9 METWLLLVISLVLLYLYGTHSHGIFKKL-GIPGPKPLPFLG-----------TILAYRKGFWEFD 61

  Fly    89 ----NKYGETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKPWFGDGLL-----ISN 144
                .|||:....:.|...::.:|:|..|:.:|....:.|.... |.|.|   .|:|     ||.
  Rat    62 KYCHKKYGKLWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNR-RNFGP---VGILKKAISISE 122

  Fly   145 GHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKAVV--ARMGLEAGKSFDVHDYMSQTTVDILLST 207
            ...|:..|.:::|||....||...|....::..:|  .|.|.|.||...:.|.....::|::.:|
  Rat   123 DEEWKRIRALLSPTFTSGKLKEMFPIINQYTDMLVRNMRQGSEEGKPTSMKDIFGAYSMDVITAT 187

  Fly   208 AMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLD---------SIYKF-TKLREKGDRMM 262
            :.||......|....:.:            ::|.|.:.|         :::.| |.|.|    .:
  Rat   188 SFGVNVDSLNNPQDPFVE------------KIKKLLKFDIFDPLFLSVTLFPFLTPLFE----AL 236

  Fly   263 NI------ILGMTSKVVKDRKENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAK 321
            |:      ::......|:..|||..:|                   ||                |
  Rat   237 NVSMFPRDVIDFFKTSVERMKENRMKE-------------------KE----------------K 266

  Fly   322 RRLALLDAMVEMAKNPDIEWNEK-----DIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAK 381
            :|:..|..|:. ::|..::.:.|     :|:.:....:|.|::|||:..||.|.::.||.|||.|
  Rat   267 QRMDFLQLMIN-SQNSKVKDSHKALSDVEIVAQSVIFIFAGYETTSSALSFVLYLLAIHPDIQKK 330

  Fly   382 VFAEQKAIFGDNMLRDCTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKG 446
            :..|..|...:.  ...|:...::|:||:.|:.|||||||....:.|....|::: :|.: :|||
  Rat   331 LQDEIDAALPNK--AHATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDVEI-NGVF-IPKG 391

  Fly   447 TTVIVLQYCVHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLL 511
            |.|::..:.:|:.|..:|.|.:|.|:.|..:...|.:.|.::||..|||:|:|.::|::.:||.|
  Rat   392 TVVMIPTFALHKDPHYWPEPEEFRPERFSKKNQDNINPYMYLPFGNGPRNCIGMRFALMNMKVAL 456

  Fly   512 STIVRNYIVH-STDTEADFKLQADIILKLE 540
            ..:::|:... ..:|:...||....:|:.|
  Rat   457 VRVLQNFSFQPCKETQIPLKLSKQGLLQPE 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	117/477 (25%)
Cyp3a9	NP_671739.2	CYP3A	67..492	CDD:410743	119/479 (25%)