Protein Alignment Cyp4g1 and Cyp3a62

DIOPT Version :10

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001019403.1
• Gene: Cyp3a62 / 170509
• RGDID: 1595919
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 544
• Identity: 131/544 - (24%)
• Similarity: 233/544 - (42%)
• Gaps: 106/544 - (19%)

  Fly    31 LVGTLVAMALYEYWRRNSREYRMVANIPSPPELPILGQAHVAAGLSNAEILAVGLGYL------- 88
            |:.|::.: ||.|.......::.: .|..|..||.:|           .|||...|:.
  Rat    14 LLATILVL-LYLYGTSTHGNFKKL-GISGPKPLPFVG-----------NILAYRHGFWEFDRHCH 65

  Fly    89 NKYGETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKPWFGDGLL-----ISNGHHW 148
            .|||:....:.|...::.:|:|..|:.:|....:.|.... |.|.|   .|:|     :|....|
  Rat    66 KKYGDIWGFYEGRQPILAITDPDIIKTVLVKECYSTFTNR-RSFGP---AGILKKAITLSEDEEW 126

  Fly   149 RHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLEA--GKSFDVHDYMSQTTVDILLSTAMGV 211
            :..|.:::|||....||...|....::..:|..:..||  |....:.|.....::|::..|:.||
  Rat   127 KRLRTLLSPTFTSGKLKEMFPIINQYADLLVKNVKHEAEKGNPITMKDIFGAYSMDVITGTSFGV 191

  Fly   212 KKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYKFTKLREKGDRMMNIILGMTSKVVKDR 276
            .                  .|.::..|...:.::..:.||
  Rat   192 N------------------VDSLNNPQNPFVQKVKKLLKF------------------------- 213

  Fly   277 KENFQEE--SRAIVEEISTPVAST------PASKKEGLRDDLDDIDENDV--GAKRRLALLDAMV 331
              ||.:.  ...|:....|||...      |....:..|..::.:.||.:  ..|:||..|..|:
  Rat   214 --NFLDPFFLSVILFPFLTPVFEAFDITVFPKDVMKFFRTSVERMKENRMQEKVKQRLDFLQLMI 276

  Fly   332 EMAKNPDIE----WNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGD 392
            ....:.|.|    ..:.:|:.:....:|.|::|||:..||||.::..|.|:|.|:..|..|...:
  Rat   277 NSQSSGDKESHQGLTDVEIVAQSIFFIFAGYETTSSALSFALYLLATHPDLQKKLQDEIDAALPN 341

  Fly   393 NMLRDCTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVH 457
            .  ...|:...:||:||:.|:.|||||:|....:.|....|::: :|.: :||||.|:|..:.:|
  Rat   342 K--APVTYDVLVEMEYLDMVLNETLRLFPVGGRLERVCKKDVEI-NGVF-IPKGTVVMVPTFALH 402

  Fly   458 RRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVHS 522
            :.|..:|.|.:|.|:.|..:...:.:.|.::||..|||:|:|.::|::.:|:.|..:::|:
  Rat   403 KDPKCWPEPEEFCPERFRKKNQDSINPYIYLPFGNGPRNCIGMRFALMNMKIALVRVLQNF---- 463

  Fly   523 TDTEADFKL--QADIILKL-ENGF 543
                 .|.|  :..|.||| :.||
  Rat   464 -----SFGLCKETQIPLKLRKKGF 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	115/476 (24%)
Cyp3a62	NP_001019403.1	CYP3A	67..492	CDD:410743	117/478 (24%)