Protein Alignment Cyp4g1 and CYP24A1

DIOPT Version :10

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_000773.2
• Gene: CYP24A1 / 1591
• HGNCID: 2602
• Length: 514
• Species: Homo sapiens
• Alignment Length: 510
• Identity: 123/510 - (24%)
• Similarity: 209/510 - (40%)
• Gaps: 102/510 - (20%)

  Fly    50 EYRMVANIPSPPELPILGQAHVAAGLSNAEILAVG---------LGYLNKYGETMKAWLGNVLLV 105
            |.:..|.:|.|...|:||        |..:||..|         :.|..|||:..:..||:...|
Human    51 ETQNAAALPGPTSWPLLG--------SLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESV 107

  Fly   106 FLTNPSDIELILSGHQHLTKAEEYRYFKPW--------FGDGLLISNGHHWRHHRKMIAPTFHQS 162
            .|.:|..:|.:........:..|   .|||        .|.||||..|..|:..|.    .|.:.
Human   108 HLGSPCLLEALYRTESAYPQRLE---IKPWKAYRDYRKEGYGLLILEGEDWQRVRS----AFQKK 165

  Fly   163 ILKSFVPTFVDHS-KAVVARMGLEAGKSFDVHDYMSQTTVDILLSTAMGVKKL-PEGNK-SFEYA 224
            ::|......:|:. ..|:|             |:|.:  :|.|......|:.| .|.|| |||
Human   166 LMKPGEVMKLDNKINEVLA-------------DFMGR--IDELCDERGHVEDLYSELNKWSFE-- 213

  Fly   225 QAVVDMCDIIHKRQVKLLYRLDSIYKFTKLREKGDRMMNIILGMTSKVVKDRKENFQEESRAIVE 289
                .:|.::::::..||.           :..||..:|.|:     .:|.....|   .|.:|
Human   214 ----SICLVLYEKRFGLLQ-----------KNAGDEAVNFIM-----AIKTMMSTF---GRMMV- 254

  Fly   290 EISTPVASTPASKKEGLRDDL--DDIDENDVGAKRRLALLDAMVE-MAKNPDIEW---------- 341
                    ||....:.|...:  |.....|...|...|.:|..:| .::.|..::
Human   255 --------TPVELHKSLNTKVWQDHTLAWDTIFKSVKACIDNRLEKYSQQPSADFLCDIYHQNRL 311

  Fly   342 NEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNMLRDCTFADTMEM 406
            ::|::...|..:.....:||:....:.|..:..:..:|.|:..|.:::..:|.:...  .|...|
Human   312 SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRA--EDLRNM 374

  Fly   407 KYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDIYPNPTKFDP 471
            .||:..:.|::||.|.||...|.||....|  |.|.:||||.:::....:....|.:.:.::|.|
Human   375 PYLKACLKESMRLTPSVPFTTRTLDKATVL--GEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRP 437

  Fly   472 DNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVHSTDTE 526
            :.:|.|: ...:.::.:||..|.|.|:||:.|.|:|.:.|..|||.|.:.:||.|
Human   438 ERWLQEK-EKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNE 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	109/459 (24%)
CYP24A1	NP_000773.2	CYP24A1	90..508	CDD:410738	111/463 (24%)