Protein Alignment Cyp4g1 and Cyp51

DIOPT Version :10

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_064394.2
• Gene: Cyp51 / 13121
• MGIID: 106040
• Length: 503
• Species: Mus musculus
• Alignment Length: 534
• Identity: 117/534 - (21%)
• Similarity: 220/534 - (41%)
• Gaps: 96/534 - (17%)

  Fly     5 VVQETLQQAASSSSTTVLGFSPMLTTLVGTLVAMAL-YEYWRRNSREYRMVANIPSPPE----LP 64
            |:.:.::|        |.|.:.:.|.|:.....::| |.:........::.|...|||.    :|
Mouse    13 VLGQAMEQ--------VTGGNLLSTLLIACAFTLSLVYLFRLAVGHMVQLPAGAKSPPHIYSPIP 69

  Fly    65 ILGQAHVAAGLSNAEILAVGLGYLNKYGETMK-AWLGNVLLVFLTNPSDIELILSGHQHLTKAEE 128
            .||.| :|.|.|..|.|.   ....|||.... ..:|......|.:.:...|..|.::.|...|.
Mouse    70 FLGHA-IAFGKSPIEFLE---NAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEEV 130

  Fly   129 Y-RYFKPWFGDGLL--ISNGHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLEAGKSF 190
            | |...|.||.|:.  :.|. .:...:|:|....:.:..|.:||.....:|......| |:|:.
Mouse   131 YGRLTTPVFGKGVAYDVPNA-IFLEQKKIIKSGLNIAHFKQYVPIIEKEAKEYFQSWG-ESGER- 192

  Fly   191 DVHDYMSQTTVDILLSTAMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYKFTKLR 255
            :|.:.:|    ::::.||                    ..|  :|.::::           ::|.
Mouse   193 NVFEALS----ELIILTA--------------------SHC--LHGKEIR-----------SQLN 220

  Fly   256 EKGDRMMNIILGMTSKVVKDRKENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGA 320
            ||           .:::..|....|...:..:...:..|    ...:::....::.:|....: .
Mouse   221 EK-----------VAQLYADLDGGFTHAAWLLPAWLPLP----SFRRRDRAHREIKNIFYKAI-Q 269

  Fly   321 KRRLA------LLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQ 379
            ||||:      :|..:::..........:::|...:..::..|..|:|..|::....:...|.:|
Mouse   270 KRRLSKEPAEDILQTLLDSTYKDGRPLTDEEISGMLIGLLLAGQHTSSTTSAWMGFFLAKDKPLQ 334

  Fly   380 AKVFAEQKAIFGDNMLRDCTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGP---- 440
            .|.:.||||:.|:: |...|:....::..|:|.|.|||||.||:..:       :::|..|
Mouse   335 EKCYLEQKAVCGED-LPPLTYDQLKDLNLLDRCIKETLRLRPPIMTM-------MRMAKTPQTVA 391

  Fly   441 -YTVPKGTTVIVLQYCVHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAM 504
             ||:|.|..|.|......|..|.:.....|:||.:|.:..|:...::::||.||...|||..:|.
Mouse   392 GYTIPPGHQVCVSPTVNQRLKDSWAERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCVGENFAY 456

  Fly   505 LKLKVLLSTIVRNY 518
            :::|.:.||::|.|
Mouse   457 VQIKTIWSTMLRLY 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	94/442 (21%)
Cyp51	NP_064394.2	CYP51-like	88..499	CDD:410668	96/447 (21%)