Protein Alignment Cyp4g1 and Cyp4a12b

DIOPT Version :10

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_758510.2
• Gene: Cyp4a12b / 13118
• MGIID: 3611747
• Length: 508
• Species: Mus musculus
• Alignment Length: 563
• Identity: 154/563 - (27%)
• Similarity: 263/563 - (46%)
• Gaps: 86/563 - (15%)

  Fly     6 VQETLQQAASSSSTTVLGFSPMLTTLVGTLVAMALYEYWRRNSREYRMVANIPSPPELPILGQAH 70
            :.|.||.|:..|          |..|:.....:.|:..|..:|.:     ..||||...:.|...
Mouse    15 ISEYLQVASVLS----------LLLLLFKTAQLYLHRQWLLSSTQ-----QFPSPPSHWLFGHKI 64

  Fly    71 VAAGLSNAEILAVGLGYLNKYGETMKAWL-GNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKP 134
                |.:.::..: |..:..:......|| |:.:.:.:.:|..::||| |.........||:..|
Mouse    65 ----LKDQDLQDI-LTRIKNFPSACPQWLWGSKVRIQVYDPDYMKLIL-GRSDPKAHGSYRFLAP 123

  Fly   135 WFGDGLLISNGHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLEAGK--SFDVHDYMS 197
            |.|.|||:.:|..|..||:|:.|.||..|||.:.....|....::.:.....|:  :.::..:::
Mouse   124 WIGRGLLLLDGQTWFQHRRMLTPAFHYDILKPYTEIMADSVHVMLDKWEQIVGQDSTLEIFQHIT 188

  Fly   198 QTTVDILLSTAM---GVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYKFTKLREKGD 259
            ..|:|.::..|.   |..:|....||  |.|||.|:.::...|...:.::.|.||:.:......:
Mouse   189 LMTLDTIMKCAFSHEGSVQLDRKYKS--YIQAVEDLNNLFFLRVRNIFHQNDIIYRVSSNGCLAN 251

  Fly   260 RMMNIILGMTSKVVKDRKENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRL 324
            ....:....|.:|:|.|:...|:|                        ::|:.:.:     ||||
Mouse   252 SACQLAHDHTDQVIKSRRSQLQDE------------------------EELEKLKK-----KRRL 287

  Fly   325 ALLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAI 389
            ..||.::..........::||:..||:|.||||||||::|.|:....:..:.:.|.:...|.:::
Mouse   288 DFLDILLFARMENGKSLSDKDLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQRCRKEIQSL 352

  Fly   390 FGDNMLRDCTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQY 454
            .||.  ...|:.|..:|.|....|.|.||:|||||.::|.|...:....| .::|||..|::..|
Mouse   353 LGDG--ASITWNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSPVTFPDG-RSLPKGIHVMLSFY 414

  Fly   455 CVHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLS-TIVRNY 518
            .:|..|.::|||..|||..|.|.  ::||.:||:|||.|.|:|:|:::||.:|||.:: |::|
Mouse   415 GLHHNPTVWPNPEVFDPSRFAPG--SSRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLR-- 475

  Fly   519 IVHSTDTEADFKLQAD----------IILKLENGFNVSLEKRQ 551
                      |:|..|          |:||.:||.::.|:|.|
Mouse   476 ----------FELLPDPTRVPIPIPRIVLKSKNGIHLHLKKLQ 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	134/469 (29%)
Cyp4a12b	NP_758510.2	CYP4B-like	70..503	CDD:410771	135/482 (28%)