Protein Alignment Cyp4g1 and Cyp46a1

DIOPT Version :10

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_034140.1
• Gene: Cyp46a1 / 13116
• MGIID: 1341877
• Length: 500
• Species: Mus musculus
• Alignment Length: 516
• Identity: 119/516 - (23%)
• Similarity: 226/516 - (43%)
• Gaps: 85/516 - (16%)

  Fly    25 SPMLTTLVGTLVAMAL-----YEYWRRNSREYRMVANIPSPP-------ELPILGQAHVAAGLSN 77
            ||.| .|:|:.|.:|.     :.:..|:..|:     ||.||       .||...:.....|...
Mouse     2 SPGL-LLLGSAVLLAFGLCCTFVHRARSRYEH-----IPGPPRPSFLLGHLPYFWKKDEDCGRVL 60

  Fly    78 AEILAVGLGYLNKYGETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKPWFGDGL-- 140
            .::.   |.:..|||..::..:.....|.:|:|..::..|...::...::.||..:..||:.|
Mouse    61 QDVF---LDWAKKYGPVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFG 122

  Fly   141 --LISNGHH--WRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLEA-GKS-FDVHDYMSQT 199
              |:|...:  |...||::...|.:|.|.|.:.||.:.::.:|..:..:| |:: ..:.|.::..
Mouse   123 QGLVSECDYGRWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTCA 187

  Fly   200 TVDILLSTAMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYKFTKLREKGDRMMNI 264
            |:|||...|.|::...........:|||..|.:.|...:       :::.||...:.|..|.:..
Mouse   188 TIDILAKAAFGMETSMLLGAQKPLSQAVKVMLEGISASR-------NTLAKFMPGKRKQLREIRE 245

  Fly   265 ILGMTSKVVKD----RKENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRLA 325
            .:.:..:|.||    |:|..:..     |::...:.:.....:||.:||
Mouse   246 SIRLLRQVGKDWVQRRREALKRG-----EDMPADILTQILKAEEGAQDD---------------- 289

  Fly   326 LLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIF 390
                              :.::|...|....||:|::...:|.:..:....:|.|::.||...:.
Mouse   290 ------------------EVLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVV 336

  Fly   391 GDNMLRDCTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYC 455
            |..  |...:.|...::||.:|:.|:||||||.....|.|:.: .|..| ..||..|.::...|.
Mouse   337 GSK--RHLDYEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEE-TLIDG-VRVPGNTPLLFSTYV 397

  Fly   456 VHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVR 516
            :.|....:.:|..|:||.|.|.  |.:..:::.|||.|.|||:|:::|.:::||:::.:::
Mouse   398 MGRMDTYFEDPLTFNPDRFGPG--APKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQ 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	100/437 (23%)
Cyp46a1	NP_034140.1	CYP46A1-like	61..484	CDD:410706	103/451 (23%)