Protein Alignment Cyp4g1 and Cyp46a1

DIOPT Version :9

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_034140.1
• Gene: Cyp46a1 / 13116
• MGIID: 1341877
• Length: 500
• Species: Mus musculus
• Alignment Length: 516
• Identity: 119/516 - (23%)
• Similarity: 226/516 - (43%)
• Gaps: 85/516 - (16%)

  Fly    25 SPMLTTLVGTLVAMAL-----YEYWRRNSREYRMVANIPSPP-------ELPILGQAHVAAGLSN 77
            ||.| .|:|:.|.:|.     :.:..|:..|:     ||.||       .||...:.....|...
Mouse     2 SPGL-LLLGSAVLLAFGLCCTFVHRARSRYEH-----IPGPPRPSFLLGHLPYFWKKDEDCGRVL 60

  Fly    78 AEILAVGLGYLNKYGETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKPWFGDGL-- 140
            .::.   |.:..|||..::..:.....|.:|:|..::..|...::...::.||..:..||:.|
Mouse    61 QDVF---LDWAKKYGPVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFG 122

  Fly   141 --LISNGHH--WRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLEA-GKS-FDVHDYMSQT 199
              |:|...:  |...||::...|.:|.|.|.:.||.:.::.:|..:..:| |:: ..:.|.::..
Mouse   123 QGLVSECDYGRWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTCA 187

  Fly   200 TVDILLSTAMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYKFTKLREKGDRMMNI 264
            |:|||...|.|::...........:|||..|.:.|...:       :::.||...:.|..|.:..
Mouse   188 TIDILAKAAFGMETSMLLGAQKPLSQAVKVMLEGISASR-------NTLAKFMPGKRKQLREIRE 245

  Fly   265 ILGMTSKVVKD----RKENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRLA 325
            .:.:..:|.||    |:|..:..     |::...:.:.....:||.:||
Mouse   246 SIRLLRQVGKDWVQRRREALKRG-----EDMPADILTQILKAEEGAQDD---------------- 289

  Fly   326 LLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIF 390
                              :.::|...|....||:|::...:|.:..:....:|.|::.||...:.
Mouse   290 ------------------EVLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVV 336

  Fly   391 GDNMLRDCTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYC 455
            |..  |...:.|...::||.:|:.|:||||||.....|.|:.: .|..| ..||..|.::...|.
Mouse   337 GSK--RHLDYEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEE-TLIDG-VRVPGNTPLLFSTYV 397

  Fly   456 VHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVR 516
            :.|....:.:|..|:||.|.|.  |.:..:::.|||.|.|||:|:::|.:::||:::.:::
Mouse   398 MGRMDTYFEDPLTFNPDRFGPG--APKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQ 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	p450	58..518	CDD:278495	109/478 (23%)
Cyp46a1	NP_034140.1	p450	34..466	CDD:278495	109/478 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000