Protein Alignment Cyp4g1 and Cyp3a16

DIOPT Version :10

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Alignment Length: 545
• Identity: 147/545 - (26%)
• Similarity: 248/545 - (45%)
• Gaps: 93/545 - (17%)

  Fly    24 FSPM-LTTLV-GTLVAMALYEYWRRNSREYRMVANIPSPPELPILGQA-HVAAGLSNAEILAVGL 85
            ||.: |.||| ..::.:.||.|.......::. ..||.|..||.||.. :...||...:     :
Mouse     4 FSALSLDTLVLLAIILVLLYRYGTCTHGLFKK-QGIPGPKPLPFLGTVLNYYKGLWKFD-----M 62

  Fly    86 GYLNKYGETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYF---KPWFGDGLL-----I 142
            ....|||:|...:.|.:.|..:|:|..|:.:|       ..|.:..|   :.:|..|::     :
Mouse    63 ECYEKYGKTWGLFDGQIPLFVITDPETIKNVL-------VKECFSVFTNRQDFFPVGIMSKSISL 120

  Fly   143 SNGHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKAVV--ARMGLEAGKSFDVHDYMSQTTVDILL 205
            :....|:.:|.:::|||....||...|....:...:|  .|...|.||...|.|.:...::|:::
Mouse   121 AKDEEWKRYRALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQEAEKGKPVAVKDVLGAYSMDVII 185

  Fly   206 STAMGVK----KLPEGNKSFEYAQAVV--DMCDIIHKRQVKLLYRLDSIYKFTKLREKGDRMMNI 264
            ||..||.    ..|| :...|.|:.|:  |..|.: ...|.|...|..||:          |:||
Mouse   186 STTFGVNIDSLNNPE-DPFVENAKKVLRFDYFDPL-SLSVALFPFLTPIYE----------MLNI 238

  Fly   265 ILGMTSKVVKDRKENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDEN--DVGAKRRLALL 327
            .:     ..||..|.|::                          .:|.:.||  |...|.|:..:
Mouse   239 CM-----FPKDSIEFFKK--------------------------FVDRMTENRLDSKQKHRVDFI 272

  Fly   328 DAMVE---MAKNPDIE--WNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQK 387
            ..|:|   .:|:.|..  .:|.:|..:....:|.|::|||:..||.:..:..|.|||.|:   |:
Mouse   273 YLMMEAYNKSKDKDSHKALSEIEITAQSIIFIFAGYETTSSILSFTVYSLATHPDIQKKL---QE 334

  Fly   388 AIFGDNMLRD---CTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTV 449
            .|  |..|.:   .|:...|.|:||:.|:.|||||||....:.|....|::: :|.| :|||:||
Mouse   335 EI--DEALPNKAPPTYDTVMAMEYLDMVLNETLRLYPITNRLQRVCKKDVEI-NGIY-IPKGSTV 395

  Fly   450 IVLQYCVHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTI 514
            |:..|.:|..|..:|.|.:|.|:.|..|...:...|.::||..|||:|:|.::|::.:|:.|..:
Mouse   396 IIPSYVLHHDPQHWPEPEEFQPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKV 460

  Fly   515 VRNYIVH-STDTEADFKLQADIILK 538
            ::|:... ..:|:...||..:::|:
Mouse   461 LQNFSFQPCKETQIPLKLSRELLLQ 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	127/474 (27%)
Cyp3a16	NP_031846.2	CYP3A	67..493	CDD:410743	129/476 (27%)