Protein Alignment Cyp4g1 and Cyp3a11

DIOPT Version :10

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Alignment Length: 542
• Identity: 145/542 - (26%)
• Similarity: 238/542 - (43%)
• Gaps: 104/542 - (19%)

  Fly    35 LVAMALYEYWRRNSREYRMV--ANIPSPPELPILGQA-HVAAGLSNAEILAVGLGYLNKYGETMK 96
            |:|::|...:|..:|::.:.  ..||.|..||.||.. :...||...:     :....|||:|..
Mouse    14 LLAISLVLLYRYGTRKHELFKKQGIPGPKPLPFLGTVLNYYKGLWKFD-----MECYKKYGKTWG 73

  Fly    97 AWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKP--WFGDGLLISNGHHWRHHRKMIAPTF 159
            .:.|...|:.:|:|..|:.:|. .:..:.....|.|.|  .....:.||....|:.:|.:::|||
Mouse    74 LFDGQTPLLAVTDPETIKNVLV-KECFSVFTNRRDFGPVGIMSKAISISKDDEWKRYRALLSPTF 137

  Fly   160 HQSILKSFVPTFVDHSKAVV--ARMGLEAGKSFDVHDYMSQTTVDILLSTAMGVKKLPEGNKSFE 222
            ....||...|....:...:|  .|...:.||...:.|.:...::|::.||:.||......|....
Mouse   138 TSGKLKEMFPVIEQYGDILVKYLRQKAKKGKPVTMKDVLGAYSMDVITSTSFGVNVDSLNNPEDP 202

  Fly   223 YAQAVVDMCDIIHKRQVKLLYRLD-------SIYKF---TKLREKGDRMMNIILGMTSKVVKDRK 277
            :.:            :.|.|.|.|       |:..|   |.:.|    |:||.:     ..||..
Mouse   203 FVE------------KAKKLLRFDFFDPLLFSVVLFPFLTPVYE----MLNICM-----FPKDSI 246

  Fly   278 ENFQ------EESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRLALLDAMVEMAKN 336
            |.|:      :|||.                              |...|.|:..|..|:....|
Mouse   247 EFFKKFVDRMKESRL------------------------------DSKQKHRVDFLQLMMNSHNN 281

  Fly   337 PDIEWNEKDIMD-EVNT----IMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNMLR 396
            ...:.:.|.:.| |:..    .:|.|::|||:..||.|..:..|.|||.|:   |..|  |..|.
Mouse   282 SKDKVSHKALSDMEITAQSIIFIFAGYETTSSTLSFTLHSLATHPDIQKKL---QDEI--DEALP 341

  Fly   397 D---CTFADTMEMKYLERVILETLRLYPPVPLIARRLD----YDLKLASGPYTVPKGTTVIVLQY 454
            :   .|:...|||:||:.|:.|||||||    ||.||:    .|::| :|.| :|||:||::..|
Mouse   342 NKAPPTYDTVMEMEYLDMVLNETLRLYP----IANRLERVCKKDVEL-NGVY-IPKGSTVMIPSY 400

  Fly   455 CVHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYI 519
            .:|..|..:..|.:|.|:.|..|...:...|.::||..|||:|:|.::|::.:|:.|:.|::|:.
Mouse   401 ALHHDPQHWSEPEEFQPERFSKENKGSIDPYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFS 465

  Fly   520 VH-STDTEADFKLQADIILKLE 540
            .. ..:|:...||....:|:.|
Mouse   466 FQPCKETQIPLKLSRQGLLQPE 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	129/482 (27%)
Cyp3a11	NP_031844.1	CYP3A	67..493	CDD:410743	131/484 (27%)