Protein Alignment Cyp4g1 and Cyp24a1

DIOPT Version :10

• Sequence 1: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_034126.1
• Gene: Cyp24a1 / 13081
• MGIID: 88593
• Length: 514
• Species: Mus musculus
• Alignment Length: 513
• Identity: 116/513 - (22%)
• Similarity: 206/513 - (40%)
• Gaps: 86/513 - (16%)

  Fly    50 EYRMVANIPSPPELPILG---QAHVAAGLSNA-EILAVGLGYLNKYGETMKAWLGNVLLVFLTNP 110
            |.|.|.::|.|...|:||   :.....||... :.||   .|..|||:..:..||:...|.|.:|
Mouse    51 ETRNVTSLPGPTNWPLLGSLLEIFWKGGLKKQHDTLA---EYHKKYGQIFRMKLGSFDSVHLGSP 112

  Fly   111 SDIE-LILSGHQHLTKAEEYRYFKPW--FGD------GLLISNGHHWRH-----HRKMIAPTFHQ 161
            |.:| |..:...|..:.|    .|||  :.|      ||:|..|..|:.     .:|::.|....
Mouse   113 SLLEALYRTESAHPQRLE----IKPWKAYRDHRNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIM 173

  Fly   162 SILKSFVPTFVDHSKAVVARMGLEAGKSFDVHDYMSQTTVD----ILLSTAMGVKKLPEGNKSFE 222
            .:.|.......|. ...:..:..|.|:..|::..:::.:.:    :|.....|:.:.....::..
Mouse   174 KLDKKINEVLADF-MGQIDELRDERGRIQDLYSELNKWSFESICLVLYEKRFGLLQKDTEEEALT 237

  Fly   223 YAQAVVDMCDIIHKRQ---VKLLYRLDSIYKFTKLREKGDRMMNIILGMTSKVVKDRKENFQEES 284
            :..|:..|.....|..   |:|..||:     ||:.:......:.|.......:..|.|.:.::.
Mouse   238 FIAAIKTMMSTFGKMMVTPVELHKRLN-----TKVWQAHTLAWDTIFKSVKPCIDHRLERYSQQP 297

  Fly   285 RAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRLALLDAMVEMAKNPDIEWNEKDIMDE 349
            .|                     |.|.||.:.|                      ..::|::...
Mouse   298 GA---------------------DFLCDIYQQD----------------------HLSKKELYAA 319

  Fly   350 VNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNMLRDCTFADTMEMKYLERVIL 414
            |..:.....:||:....:.|..:..:..:|.::..|.:::..||.....  .|...|.||:..:.
Mouse   320 VTELQLAAVETTANSLMWILYNLSRNPQVQQRLLREIQSVLPDNQTPRA--EDVRNMPYLKACLK 382

  Fly   415 ETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDIYPNPTKFDPDNFLPERM 479
            |::||.|.||...|.||....|  |.||:||||.:.:....:....|.:.:..||.|:.:| |:.
Mouse   383 ESMRLTPSVPFTTRTLDKPTVL--GEYTLPKGTVLTLNTQVLGSSEDNFEDADKFRPERWL-EKE 444

  Fly   480 ANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVHSTDTEADFKLQADIIL 537
            ...:.::.:||..|.|.|:||:.|.|:|.:.|..|::.|.:.:||:|....|...|::
Mouse   445 KKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIIQKYNIVATDSEPVEMLHLGILV 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	101/467 (22%)
Cyp24a1	NP_034126.1	CYP24A1	90..508	CDD:410738	103/471 (22%)