DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ase and Tcf23

DIOPT Version :9

Sequence 1:NP_476694.1 Gene:ase / 30985 FlyBaseID:FBgn0000137 Length:486 Species:Drosophila melanogaster
Sequence 2:XP_006504158.1 Gene:Tcf23 / 69852 MGIID:1934960 Length:216 Species:Mus musculus


Alignment Length:223 Identity:55/223 - (24%)
Similarity:81/223 - (36%) Gaps:70/223 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    92 LGESQKQNRHNQQNQQL-SKTSVPAKKCKTNKKLAVERPPKAGTISHPHKSQSDQSFGTP-GRKG 154
            ||..:|::|.|:..|.| ..||      .:|.:|:.......||          ::.||. ||. 
Mouse    27 LGTDRKRSRINRTRQDLWEDTS------WSNHRLSRATSAPRGT----------RARGTAHGRS- 74

  Fly   155 LPLPQAVARRNARERNRVKQVNNGFALLREKIPEEVSEAFEAQGAGRGASKKLSKVETLRMAVEY 219
                :|.....||||.|||.:...|..|:..:|....:.            ||||::.|.:|..|
Mouse    75 ----EASPENAARERTRVKTLRQAFLALQAALPAVPPDT------------KLSKLDVLVLATSY 123

  Fly   220 IRSLEKLLGFDFP--------------------PLNSQGNSSGSGD---DSFMFIKDEFDCLDEH 261
            |..|.:.||.:.|                    |:.|:..:.|.|.   ||...|.....|.|. 
Mouse   124 IAHLTRTLGHELPGPAWPPFVRGLRYLHPLKKWPMRSRLYAGGLGCSDLDSTTAITTGQRCKDA- 187

  Fly   262 FDDSLSNYEMDEQQTVQQTLSEDMLNPP 289
                    |:..|.:|   .:|.:|..|
Mouse   188 --------ELGSQDSV---AAESLLTSP 204

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
aseNP_476694.1 HLH <172..224 CDD:278439 13/51 (25%)
Tcf23XP_006504158.1 bHLH_TS_TCF23_OUT 77..132 CDD:381552 19/66 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4029
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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