DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ase and ASCL3

DIOPT Version :9

Sequence 1:NP_476694.1 Gene:ase / 30985 FlyBaseID:FBgn0000137 Length:486 Species:Drosophila melanogaster
Sequence 2:NP_065697.1 Gene:ASCL3 / 56676 HGNCID:740 Length:181 Species:Homo sapiens


Alignment Length:113 Identity:41/113 - (36%)
Similarity:56/113 - (49%) Gaps:24/113 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   130 PKAGTISHPHKSQSDQSFGTPGRKGLPLPQAVARRNARERNRVKQVNNGFALLREKIPEEVSEAF 194
            |.:..:.:|:....:.|:|         |....:||.|||.|||.||.|:|.||..:|||..|  
Human    73 PFSFPMPYPNYRGCEYSYG---------PAFTRKRNERERQRVKCVNEGYAQLRHHLPEEYLE-- 126

  Fly   195 EAQGAGRGASKKLSKVETLRMAVEYIRSLEKLLGFDFPPLNSQGNSSG 242
                      |:||||||||.|::||..|:.||   :|......|:.|
Human   127 ----------KRLSKVETLRAAIKYINYLQSLL---YPDKAETKNNPG 161

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
aseNP_476694.1 HLH <172..224 CDD:278439 24/51 (47%)
ASCL3NP_065697.1 HLH 99..149 CDD:197674 30/61 (49%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165158175
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4029
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3926
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.770

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