DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ase and Mesp1

DIOPT Version :9

Sequence 1:	NP_476694.1	Gene:	ase / 30985	FlyBaseID:	FBgn0000137	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001101001.1	Gene:	Mesp1 / 308766	RGDID:	1311751	Length:	242	Species:	Rattus norvegicus

Alignment Length:	245	Identity:	54/245 - (22%)
Similarity:	80/245 - (32%)	Gaps:	108/245 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 SKTSVPAKKCKTNKKLAVERPPKAGTISHPHKSQSDQSFGTPGRKG-----LPLPQAVARRNARE 168
            ::.|.||..|        .||.:..              |||||:|     |...|   |::|.|
  Rat    44 AQASSPALPC--------ARPARRA--------------GTPGRRGTHGSRLGSGQ---RQSASE 83

  Fly   169 RNRVKQVNNGFAL--LREKIPEEVSEAFEAQGAGRGASKKLSKVETLRMAVEYIRSLEKLLGFD- 230
            |.:::......||  ||..:|..|:.          ..:.|:|:||||:|:.||..|..:||..
  Rat    84 REKLRMRTLARALHELRRFLPPSVAP----------IGQNLTKIETLRLAIRYIGHLSAVLGLSE 138

  Fly   231 --------------------------------FPPLNSQGNSSGSG-------------DDSFMF 250
                                            ..|:...|.|.||.             |.||::
  Rat   139 DSLRQQRHAVSPRGCPLCPDSGLAQAQSLGPHLSPVACSGVSWGSSPAYPRPRVAAESWDPSFLY 203

  Fly   251 IKDEFDCLDEHFDDSLSNYEMDEQQTVQQTLSEDMLNPPQASDLLPSLTT 300
            .:..          ||...||:...:          :|..:||:|..|.|
  Rat   204 TETA----------SLERQEMEPSPS----------SPLFSSDMLALLET 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ase	NP_476694.1	HLH	<172..224	CDD:278439	15/53 (28%)
Mesp1	NP_001101001.1	HLH	77..130	CDD:278439	20/65 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810