DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ase and Lyl1

DIOPT Version :9

Sequence 1:	NP_476694.1	Gene:	ase / 30985	FlyBaseID:	FBgn0000137	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001007678.1	Gene:	Lyl1 / 304663	RGDID:	1359244	Length:	278	Species:	Rattus norvegicus

Alignment Length:	138	Identity:	44/138 - (31%)
Similarity:	57/138 - (41%)	Gaps:	35/138 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 PPKAGTISHPHKSQSDQSFG---------------TPGRKGLPL-----PQAVARR---NARERN 170
            ||......|||...:....|               .|....|.|     ||.||||   |:|||.
  Rat    96 PPTLALHYHPHPFLNSVYIGPAGPFSIFPNSRLKRRPSHGELDLVDGHQPQKVARRVFTNSRERW 160

  Fly   171 RVKQVNNGFALLREKIPEEVSEAFEAQGAGRGASKKLSKVETLRMAVEYIRSLEKLLGFDFPPLN 235
            |.:.||..||.||:.:|....:            :||||.|.||:|::||..|.:||......|.
  Rat   161 RQQHVNGAFAELRKLLPTHPPD------------RKLSKNEVLRLAMKYIGFLVRLLRDQAAVLA 213

  Fly   236 SQGNSSGS 243
            |..::.||
  Rat   214 SGPSAPGS 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ase	NP_476694.1	HLH	<172..224	CDD:278439	17/51 (33%)
Lyl1	NP_001007678.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..52
		HLH	155..207	CDD:197674	25/63 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	213..278		3/9 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810