DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ase and PTF1A

DIOPT Version :9

Sequence 1:NP_476694.1 Gene:ase / 30985 FlyBaseID:FBgn0000137 Length:486 Species:Drosophila melanogaster
Sequence 2:NP_835455.1 Gene:PTF1A / 256297 HGNCID:23734 Length:328 Species:Homo sapiens


Alignment Length:93 Identity:33/93 - (35%)
Similarity:44/93 - (47%) Gaps:14/93 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   152 RKGLPLPQAVARRNARERNRVKQVNNGFALLREKIPEEVSEAFEAQGAGRGASKKLSKVETLRMA 216
            |....|.|.....|.|||.|::.:|:.|..||..||....|            |:||||:|||:|
Human   156 RSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYE------------KRLSKVDTLRLA 208

  Fly   217 VEYIRSLEKLLGFDFPPLNSQGNSSGSG 244
            :.||..|.:|:..|.|...  |.:.|.|
Human   209 IGYINFLSELVQADLPLRG--GGAGGCG 234

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
aseNP_476694.1 HLH <172..224 CDD:278439 18/51 (35%)
PTF1ANP_835455.1 HLH 165..220 CDD:238036 25/66 (38%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 259..278
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 305..328
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4029
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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