DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ase and hlh-14

DIOPT Version :9

Sequence 1:	NP_476694.1	Gene:	ase / 30985	FlyBaseID:	FBgn0000137	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_495131.3	Gene:	hlh-14 / 182758	WormBaseID:	WBGene00001958	Length:	148	Species:	Caenorhabditis elegans

Alignment Length:	218	Identity:	53/218 - (24%)
Similarity:	79/218 - (36%)	Gaps:	89/218 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 RNARERNRVKQVNNGFALLREKIPEEVSEAFEAQGAGRGASKKLSKVETLRMAVEYIRSLEKLLG 228
            ||.|||.||.|||:||.:||.::..            :..:||.||.:|||.||:||:.|:.||.
Worm     9 RNERERKRVHQVNHGFDVLRNRLQP------------KNHTKKWSKADTLREAVKYIQQLQVLLN 61

  Fly   229 FDFPPLNSQGNSSGSGDDSFMFIKDEFDCLDEHFDDSLSNYEMDEQQTV---QQTLSEDMLNPPQ 290
            .|    ..|.:.|.|..|..|...:.|           :||.:.|:.::   |....::.::.|.
Worm    62 QD----PQQPSVSSSTPDYTMNNSNNF-----------NNYAVKEEFSMYLPQNYCPQNQMSVPH 111

  Fly   291 ASDLLPSLTTLNGLQYIRIPGTNTYQLLTTDLLGDLSHEQKLEETAASGQLSRSPVPQKVVRSPC 355
                                             ||:||.                         .
Worm   112 ---------------------------------GDVSHN-------------------------F 118

  Fly   356 SSPVSPVASTELLLQTQTCATPL 378
            :||.|.|:|:. ...||.|..|:
Worm   119 NSPTSSVSSSS-YSPTQMCYPPV 140

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ase	NP_476694.1	HLH	<172..224	CDD:278439	19/51 (37%)
hlh-14	NP_495131.3	bHLH_SF	9..60	CDD:381792	26/62 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14646
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770