DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ase and Mesp1

DIOPT Version :9

Sequence 1:	NP_476694.1	Gene:	ase / 30985	FlyBaseID:	FBgn0000137	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_032614.2	Gene:	Mesp1 / 17292	MGIID:	107785	Length:	243	Species:	Mus musculus

Alignment Length:	136	Identity:	38/136 - (27%)
Similarity:	55/136 - (40%)	Gaps:	42/136 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 SKTSVPAKKCKTNKKLAVERPPKAGTISHPHKSQSDQSFGTPGRKG-----LPLPQAVARRNARE 168
            ::.|.||..|        .||.:..              |||||:|     |...|   |::|.|
Mouse    44 AQASSPAPPC--------ARPARRA--------------GTPGRRGTHGSRLGSGQ---RQSASE 83

  Fly   169 RNRVKQVNNGFAL--LREKIPEEVSEAFEAQGAGRGASKKLSKVETLRMAVEYIRSLEKLLGFDF 231
            |.:::......||  ||..:|..|:.          ..:.|:|:||||:|:.||..|..:||...
Mouse    84 REKLRMRTLARALHELRRFLPPSVAP----------TGQNLTKIETLRLAIRYIGHLSAVLGLSE 138

  Fly   232 PPLNSQ 237
            ..|..|
Mouse   139 DNLRRQ 144

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ase	NP_476694.1	HLH	<172..224	CDD:278439	15/53 (28%)
Mesp1	NP_032614.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..86		18/66 (27%)
		HLH	77..130	CDD:278439	20/65 (31%)
		CPLCP	153..157
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	204..228
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900