Protein Alignment ase and Ascl2

DIOPT Version :9

• Sequence 1: NP_476694.1
• Gene: ase / 30985
• FlyBaseID: FBgn0000137
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_032580.2
• Gene: Ascl2 / 17173
• MGIID: 96920
• Length: 263
• Species: Mus musculus
• Alignment Length: 257
• Identity: 68/257 - (26%)
• Similarity: 82/257 - (31%)
• Gaps: 133/257 - (51%)

  Fly   160 AVARRNARERNRVKQVNNGFALLREKIPEEVSEAFEAQGAGRGASKKLSKVETLRMAVEYIRSLE 224
            ||||||.|||||||.||.||..||:.:|.            .||:||||||||||.||||||:|:
Mouse   119 AVARRNERERNRVKLVNLGFQALRQHVPH------------GGANKKLSKVETLRSAVEYIRALQ 171

  Fly   225 KLLGFDFPPLNSQGNSSGSGDDSFMFIKDEFDCLDEHFDDSLSNYEMDEQQTVQQTLSEDMLNP- 288
            :||.                                            |...|:..|:..:|.|
Mouse   172 RLLA--------------------------------------------EHDAVRAALAGGLLTPA 192

  Fly   289 ---------PQASDLLPSLTTLNGLQYIRIPGTNTYQLLTTDLLGDLSHEQKLEETAASGQLSRS 344
                     |.||....||:.                                        .|.|
Mouse   193 TPPSDECAQPSASPASASLSC----------------------------------------ASTS 217

  Fly   345 PVPQKVVRSPCSSPVSPVASTELLLQTQTCATPLQQQVIKQEYVSTNISSSSNAQTSPQQQQ 406
            |.|.   |..||.|.||                      :..|.|.  .||...:.||.:|:
Mouse   218 PSPD---RLGCSEPTSP----------------------RSAYSSE--ESSCEGELSPMEQE 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ase	NP_476694.1	HLH	<172..224	CDD:278439	27/51 (53%)
Ascl2	NP_032580.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..126		6/6 (100%)
		HLH	134..176	CDD:197674	28/97 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..248		19/120 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848568
Domainoid	1	1.000	67	1.000	Domainoid score	I9760
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm11115
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13935
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.890