Protein Alignment ase and TCF23

DIOPT Version :9

• Sequence 1: NP_476694.1
• Gene: ase / 30985
• FlyBaseID: FBgn0000137
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_786951.1
• Gene: TCF23 / 150921
• HGNCID: 18602
• Length: 214
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 63/285 - (22%)
• Similarity: 92/285 - (32%)
• Gaps: 118/285 - (41%)

  Fly    86 SQRKR-------PLGESQKQNR------HNQQNQQLSKTSVPAKKCKTNKKLAVERPPKAGTISH 137
            ||||.       .:|.||.|.:      .:::..:||:|               .:.|      .
Human     2 SQRKARGPPAMPGVGHSQTQAKARLLPGADRKRSRLSRT---------------RQDP------W 45

  Fly   138 PHKSQSDQ--SFGTPGRKG-------LPLPQAVARRNARERNRVKQVNNGFALLREKIPEEVSEA 193
            ..:|.|:|  |..|||.:|       |...:|.....||||:||:.:...|..|:..:|....:.
Human    46 EERSWSNQRWSRATPGPRGTRAGGLALGRSEASPENAARERSRVRTLRQAFLALQAALPAVPPDT 110

  Fly   194 FEAQGAGRGASKKLSKVETLRMAVEYIRSLEKLLGFDFP--------------------PLNSQG 238
                        ||||::.|.:|..||..|.:.||.:.|                    |:.|:.
Human   111 ------------KLSKLDVLVLAASYIAHLTRTLGHELPGPAWPPFLRGLRYLHPLKKWPMRSRL 163

  Fly   239 NSSGSGDDSFMFIKDEFDCLDEHFDDSLSNYEMDEQQTVQQTLSEDMLNPPQASDLLPSLTTLNG 303
            .:.|.|                        |. |...|...|               ||..|.:.
Human   164 YAGGLG------------------------YS-DLDSTTAST---------------PSQRTRDA 188

  Fly   304 LQYIRIPGTNTYQLLTTDL---LGD 325
            ....::||.....|.||.|   |||
Human   189 EVGSQVPGEADALLSTTPLSPALGD 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ase	NP_476694.1	HLH	<172..224	CDD:278439	12/51 (24%)
TCF23	NP_786951.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..86		24/104 (23%)
		HLH	83..132	CDD:197674	18/60 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..214		14/55 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900