Protein Alignment ase and ASCL4

DIOPT Version :9

• Sequence 1: NP_476694.1
• Gene: ase / 30985
• FlyBaseID: FBgn0000137
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_982260.3
• Gene: ASCL4 / 121549
• HGNCID: 24311
• Length: 172
• Species: Homo sapiens
• Alignment Length: 114
• Identity: 42/114 - (36%)
• Similarity: 59/114 - (51%)
• Gaps: 29/114 - (25%)

  Fly   151 GRKGLPLPQAVA-------RRNARERNRVKQVNNGFALLREKIPEEVSEAFEAQGAGRGASKKLS 208
            |.:.||:|...|       :||.|||.||:.||.|:|.||:.:|.|:            |.|:||
Human    57 GWQYLPVPLDSAFEPAFLRKRNERERQRVRCVNEGYARLRDHLPREL------------ADKRLS 109

  Fly   209 KVETLRMAVEYIRSLEKLL-----GFD-----FPPLNSQGNSSGSGDDS 247
            ||||||.|::||:.|::||     |.:     .|...::.||.|....|
Human   110 KVETLRAAIDYIKHLQELLERQAWGLEGAAGAVPQRRAECNSDGESKAS 158

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ase	NP_476694.1	HLH	<172..224	CDD:278439	22/51 (43%)
ASCL4	NP_982260.3	bHLH_SF	66..129	CDD:412148	31/74 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	144..172		4/15 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158177
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3926
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.770