DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ase and ascl2

DIOPT Version :9

Sequence 1:	NP_476694.1	Gene:	ase / 30985	FlyBaseID:	FBgn0000137	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	XP_002940290.3	Gene:	ascl2 / 100494131	XenbaseID:	XB-GENE-6458615	Length:	236	Species:	Xenopus tropicalis

Alignment Length:	171	Identity:	61/171 - (35%)
Similarity:	77/171 - (45%)	Gaps:	45/171 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 RHNQQNQQLSKTSVPAKKCKTNKKLAV----------------ERPPKAGTISHPHK----SQSD 144
            ||| :.:...:..||:......|...|                |||.||     |.|    |.|.
Frog    33 RHN-KGKSFQREQVPSGPTLERKATPVVPVAPPSSAMEEQPGSERPAKA-----PRKVANQSGSP 91

  Fly   145 QSFGTPGRKGLPLPQAVA------RRNARERNRVKQVNNGFALLREKIPEEVSEAFEAQGAGRGA 203
            |......|.| .||.|:.      |||.|||||||.||.|||.||:.:|:           .:|.
Frog    92 QRLRCQRRSG-SLPNAIGISATSERRNERERNRVKLVNLGFAKLRQHVPQ-----------AQGP 144

  Fly   204 SKKLSKVETLRMAVEYIRSLEKLLGFDFPPLNSQGNSSGSG 244
            :||:|||||||.||||||:|:.:| .:......||.:...|
Frog   145 NKKMSKVETLRSAVEYIRALQSIL-MERTAGEGQGRAGSDG 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ase	NP_476694.1	HLH	<172..224	CDD:278439	26/51 (51%)
ascl2	XP_002940290.3	bHLH_TS_ASCL2_Mash2	110..174	CDD:381586	36/75 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	72	1.000	Domainoid score	I9148
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1131543at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9527
Panther	1	1.100	-	-	O	PTHR13935
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3926
SonicParanoid	1	1.000	-	-		X11783
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.140