Protein Alignment Pgcl and NAPSA

DIOPT Version :10

• Sequence 1: NP_525030.1
• Gene: Pgcl / 30984
• FlyBaseID: FBgn0011822
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_004842.1
• Gene: NAPSA / 9476
• HGNCID: 13395
• Length: 420
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 142/339 - (41%)
• Similarity: 185/339 - (54%)
• Gaps: 26/339 - (7%)

  Fly    69 LSNYDNFQYYGNISIGTPGQDFLVQFDTGSSNLWVPGSSC--ISTACQDHQVFYKNKSSTYVANG 131
            ||||.:.||:|.|.:|||.|:|.|.|||||||||||...|  .|..|..|..|....||::.|||
Human    70 LSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANG 134

  Fly   132 TAFSITYGTGSVSGYLSVDCVGFAGLTIQSQTFGEVTTEQGTNFVDAYFDGILGMGFPSLAVDGV 196
            |.|:|.||||.|.|.||.|.:...|:...|..|||...|....|..|:||||||:|||.|:|:||
Human   135 TKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEGV 199

  Fly   197 TPTFQNMMQQGLVQSPVFSFFL-RDNGSVTFYGGELILGGSDPSLYSGSLTYVNVVQAAYWKFQT 260
            .|....:::|||:..|||||:| ||.....  ||||:||||||:.|...||:|.|...|||:...
Human   200 RPPMDVLVEQGLLDKPVFSFYLNRDPEEPD--GGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHM 262

  Fly   261 DYIKVGS--TSISTFAQAIADTGTSLIIAP----QAQYDQISQLFNANSEGLFECSS-TSYPDLI 318
            :.:|||.  |..:....||.|||||||..|    :|.:..|..:.....|.:..||. ...|.:.
Human   263 ERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALHAAIGGIPLLAGEYIILCSEIPKLPAVS 327

  Fly   319 ININGVDFKIPAKYYIIEEE----DFCSLAIQSIN-----QDFWIMGDVFLGRIYTEFDVGNQRL 374
            ..:.||.|.:.|..|:|:..    ..|....|:::     ..|||:||||||.....||.|:.:
Human   328 FLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPPPAGPFWILGDVFLGTYVAVFDRGDMK- 391

  Fly   375 GFAPVNSAVGLRKA 388
                .::.|||.:|
Human   392 ----SSARVGLARA 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgcl	NP_525030.1	Asp	76..379	CDD:394983	134/321 (42%)
NAPSA	NP_004842.1	pepsin_retropepsin_like	72..399	CDD:472175	138/333 (41%)