Protein Alignment Pgcl and YPS7

DIOPT Version :9

• Sequence 1: NP_525030.1
• Gene: Pgcl / 30984
• FlyBaseID: FBgn0011822
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_010636.1
• Gene: YPS7 / 851950
• SGDID: S000002757
• Length: 596
• Species: Saccharomyces cerevisiae
• Alignment Length: 407
• Identity: 86/407 - (21%)
• Similarity: 153/407 - (37%)
• Gaps: 94/407 - (23%)

  Fly    60 TANGYPMEHLSNYDNFQYYGNISIGTPGQDFLVQFDTGSSNLWVPGSSCISTACQDHQ----VFY 120
            |...:|:..:.......||.|.:.|||||...:..|     :..|..:.:|...:.|.    |::
Yeast    39 TEEPFPVLAVGKDGRGNYYVNSTFGTPGQRQRLLVD-----IIQPYINLVSGTSESHNEYSGVYH 98

  Fly   121 K--------NKSSTYVANGTAFSITYGTG-SVSGYLSVDCVGFAGLTIQSQTFGEVT----TEQG 172
            |        :.||..|:.|..:.|::..| :|:..|..|.:.|..::.::.:...:|    |...
Yeast    99 KHPSYLMNDSTSSVPVSPGQIYEISFIDGRAVNCTLVTDDMNFTNVSSENSSTALITDLMVTRDN 163

  Fly   173 TNFVD--------AYFD---------GILGMG----FPSLAVDGVTPTFQN-----MMQQGLVQS 211
            ..|..        ::||         |:||:.    .|..|:|....|.|:     :....:::|
Yeast   164 VQFNSGSLSISNVSFFDIQSSNFKTSGLLGLSGKVTNPGNAIDSSQYTEQSYFLSLLKDADIIES 228

  Fly   212 PVFSFFLR-DNGSVTFYG------GELILGGSDPSLYSGSL------TYV----NVVQAAY---- 255
            ..:|.:|. |..:...|.      |:|:|||.||||::|:|      .||    |.|...|
Yeast   229 SSYSLWLAGDTSTYKTYRDPISNCGKLLLGGVDPSLFTGTLGKFDLIPYVDPVSNAVSVGYPIVP 293

  Fly   256 ----WKFQTDYIKVGSTSISTFAQAIADTGTSLIIAPQAQYDQISQLFNAN-----SEGLFECSS 311
                :........:..||....:.|:.|:.:|:...|.:...||:....|.     ...|.:||.
Yeast   294 LGPIYIVSNSGQSLNMTSKDFLSPALLDSTSSVSYLPTSTIIQIAVQIAATYVESLDRWLVQCSI 358

  Fly   312 TS--------YPDLIINI-------NGVDFKIPAKYYIIEEEDFCSLAI-QSINQDFWIMGDVFL 360
            ..        ..:|.|.|       :..|....:..:....::.|.|.: .:.|....|:|:.|:
Yeast   359 ADMGVSLGFRLRELTIEIPLRDLLSSTYDTSTNSSMFFSSGQEACFLTLYANTNTGVNILGEAFI 423

  Fly   361 GRIYTEFDVGNQRLGFA 377
            ..||...|:.:..:..|
Yeast   424 KNIYMAMDLEDNTIAIA 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgcl	NP_525030.1	pepsin_retropepsin_like	67..378	CDD:299705	84/400 (21%)
		Asp	76..379	CDD:278455	84/391 (21%)
YPS7	NP_010636.1	pepsin_retropepsin_like	162..442	CDD:416259	58/279 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341772
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740