Protein Alignment Pgcl and MKC7

DIOPT Version :9

• Sequence 1: NP_525030.1
• Gene: Pgcl / 30984
• FlyBaseID: FBgn0011822
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_010428.3
• Gene: MKC7 / 851722
• SGDID: S000002551
• Length: 596
• Species: Saccharomyces cerevisiae
• Alignment Length: 451
• Identity: 103/451 - (22%)
• Similarity: 163/451 - (36%)
• Gaps: 135/451 - (29%)

  Fly    50 FVQQKYNRQYTA-------------------NGYPMEHLSNYDNFQYYGNISIGTPGQDFLVQFD 95
            :|:..:.::|.:                   :.|.:..|:|.::| |...:.||||.|...|..|
Yeast    36 YVKMNFQKKYGSSFENALDDTKGRTRLMTRDDDYELVELTNQNSF-YSVELDIGTPPQKVTVLVD 99

  Fly    96 TGSSNLWVPGS----------------------------------------------------SC 108
            ||||:|||.||                                                    |.
Yeast   100 TGSSDLWVTGSDNPYCSTKKKDTTGSSFKQVNKDALASVVESVFTEISYDTTIVTSEATATFDST 164

  Fly   109 ISTA----CQDHQVFYKNKSSTYVANGTAFSITYG-TGSVSGYLSVDCVGFAGLTIQSQTFGEVT 168
            .||:    |..:..|..:||||:.:|.|.|||.|| |...||....|.:....|.|...:|. |.
Yeast   165 ASTSQLIDCATYGTFNTSKSSTFNSNNTEFSIAYGDTTFASGTWGHDQLSLNDLNITGLSFA-VA 228

  Fly   169 TEQGTNFVDAYFDGILGMGFPSL--AVDGV-------TPTFQN----MMQQGLVQSPVFSFFLRD 220
            .|..:..      |:||:|.|.|  ...||       :.|:.|    :...|:::|..:|.|..|
Yeast   229 NETNSTV------GVLGIGLPGLESTYSGVSLSSVQKSYTYNNFPMVLKNSGVIKSTAYSLFAND 287

  Fly   221 NGSVTFYGGELILGGSDPSLYSGSL---TYVNVVQAAYWK----FQTDYIKVG----------ST 268
            :.|   ..|.::.|..|...|:|.|   ..:|.:|...:|    ||.....:|          :|
Yeast   288 SDS---KHGTILFGAVDHGKYAGDLYTIPIINTLQHRGYKDPIQFQVTLQGLGTSKGDKEDNLTT 349

  Fly   269 SISTFAQAIADTGTSLIIAP----QAQYDQISQLF-NANSEGLFEC--SSTSYPDLIININGV-- 324
            ..:|....:.|:||::...|    :...||:...: :|....:.:|  .......:|.:..|.
Yeast   350 LTTTKIPVLLDSGTTISYMPTELVKMLADQVGATYSSAYGYYIMDCIKEMEEESSIIFDFGGFYL 414

  Fly   325 -----DFKIPAKYYIIEEEDFCSLAIQSINQDFWIMGDVFLGRIYTEFDVGNQRLGFAPVN 380
                 ||::...    ...:.|.|.|...:....|:||.||...|..:|:.|..:..|..|
Yeast   415 SNWLSDFQLVTD----SRSNICILGIAPQSDPTIILGDNFLANTYVVYDLDNMEISMAQAN 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgcl	NP_525030.1	pepsin_retropepsin_like	67..378	CDD:299705	98/411 (24%)
		Asp	76..379	CDD:278455	96/403 (24%)
MKC7	NP_010428.3	SAP_like	79..470	CDD:133141	97/405 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341769
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.700