Protein Alignment Pgcl and YPS1

DIOPT Version :9

• Sequence 1: NP_525030.1
• Gene: Pgcl / 30984
• FlyBaseID: FBgn0011822
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_013221.1
• Gene: YPS1 / 850811
• SGDID: S000004110
• Length: 569
• Species: Saccharomyces cerevisiae
• Alignment Length: 459
• Identity: 105/459 - (22%)
• Similarity: 176/459 - (38%)
• Gaps: 118/459 - (25%)

  Fly    21 EANSTLRRIPIQKSPNFKRSHKNIVAERDFVQQKYNRQYTANGYPMEHLSNYDNFQYYGNISIGT 85
            ::||...::|..|.  :..|.:|:.:::....:...|   |:||....::|..:| |..::.:||
Yeast    33 DSNSKFVKLPFHKL--YGDSLENVGSDKKPEVRLLKR---ADGYEEIIITNQQSF-YSVDLEVGT 91

  Fly    86 PGQDFLVQFDTGSSNLWVPGSS---CISTA----------------------------------- 112
            |.|:..|..|||||:||:.||.   |.|.:
Yeast    92 PPQNVTVLVDTGSSDLWIMGSDNPYCSSNSMGSSRRRVIDKRDDSSSGGSLINDINPFGWLTGTG 156

  Fly   113 -----------------------------CQDHQVFYKNKSSTYVANGTAFSITYGTGS-VSGYL 147
                                         ||.:..|..:.|||:.:|.|.|||:||.|: .||..
Yeast   157 SAIGPTATGLGGGSGTATQSVPASEATMDCQQYGTFSTSGSSTFRSNNTYFSISYGDGTFASGTF 221

  Fly   148 SVDCVGFAGLTIQSQTFGEVTTEQGTNFVDAYFDGILGMGFPSLAV---------DGVTPTFQN- 202
            ..|.:..:.|.:...:|. |..|..:..      |:||:|.|.|.|         .|....:.|
Yeast   222 GTDVLDLSDLNVTGLSFA-VANETNSTM------GVLGIGLPELEVTYSGSTASHSGKAYKYDNF 279

  Fly   203 ---MMQQGLVQSPVFSFFLRDNGSVTFYGGELILGGSDPSLYSGSL---TYVNVVQAAYW----K 257
               :...|.::|..:|.:|.|:.::   .|.::.|..|.|.|:|:|   ..||.:.|:.:    :
Yeast   280 PIVLKNSGAIKSNTYSLYLNDSDAM---HGTILFGAVDHSKYTGTLYTIPIVNTLSASGFSSPIQ 341

  Fly   258 FQTDYIKVG--------STSISTFAQAIADTGTSLIIAPQAQYDQISQLFNANSEG-----LFEC 309
            |......:|        .|..:|...|:.|:||:|...||.....|:....|....     :.:|
Yeast   342 FDVTINGIGISDSGSSNKTLTTTKIPALLDSGTTLTYLPQTVVSMIATELGAQYSSRIGYYVLDC 406

  Fly   310 SSTSYPDLIININGVDFKIPAKYYIIEEEDFCSLAIQSINQDF-WIMGDVFLGRIYTEFDVGNQR 373
            .|....:::.:..|.....|...:|:.....|.|.|...:.|. .|:||.||...|..:|:.|..
Yeast   407 PSDDSMEIVFDFGGFHINAPLSSFILSTGTTCLLGIIPTSDDTGTILGDSFLTNAYVVYDLENLE 471

  Fly   374 LGFA 377
            :..|
Yeast   472 ISMA 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgcl	NP_525030.1	pepsin_retropepsin_like	67..378	CDD:299705	95/413 (23%)
		Asp	76..379	CDD:278455	93/404 (23%)
YPS1	NP_013221.1	SAP_like	81..477	CDD:133141	94/406 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341770
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.700