DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgcl and AT1G62290

DIOPT Version :9

Sequence 1:	NP_525030.1	Gene:	Pgcl / 30984	FlyBaseID:	FBgn0011822	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001031219.1	Gene:	AT1G62290 / 842526	AraportID:	AT1G62290	Length:	513	Species:	Arabidopsis thaliana

Alignment Length:	432	Identity:	139/432 - (32%)
Similarity:	190/432 - (43%)	Gaps:	125/432 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 LSNYDNFQYYGNISIGTPGQDFLVQFDTGSSNLWVPGSSC-ISTACQDHQVFYKNKSSTYVANGT 132
            |.||.:.||||.|:||||.|.|.|.|||||||||||...| .|.:|..|..:..::||||..:|.
plant    81 LKNYLDAQYYGEIAIGTPPQKFTVIFDTGSSNLWVPSGKCFFSLSCYFHAKYKSSRSSTYKKSGK 145

  Fly   133 AFSITYGTGSVSGYLSVDCVGFAGLTIQSQTFGEVTTEQGTNFVDAYFDGILGMGFPSLAVDGVT 197
            ..:|.||:||:||:.|.|.|....|.::.|.|.|.|:|.|..|:.|.|||:||:||..:||...|
plant   146 RAAIHYGSGSISGFFSYDAVTVGDLVVKDQEFIETTSEPGLTFLVAKFDGLLGLGFQEIAVGNAT 210

  Fly   198 PTFQNMMQQGLVQSPVFSFFL-RDNGSVTFYGGELILGGSDPSLYSGSLTYVNVVQAAYWKFQTD 261
            |.:.||::|||::.|||||:| ||..|..  |||::.||.||..:.|..|:|.|.|..||:|...
plant   211 PVWYNMLKQGLIKRPVFSFWLNRDPKSEE--GGEIVFGGVDPKHFRGEHTFVPVTQRGYWQFDMG 273

  Fly   262 YIKVGSTS---ISTFAQAIADTGTSLIIAPQA------------------------QYDQI---- 295
            .:.:...|   ..:...||||:||||:..|.|                        ||.|.
plant   274 EVLIAGESTGYCGSGCSAIADSGTSLLAGPTAVVAMINKAIGASGVVSQQCKTVVDQYGQTILDL 338

  Fly   296 ------------------------------------------------------------SQLF- 299
                                                                        |||.
plant   339 LLAETQPKKICSQIGLCAYDGTHGVSMGIESVVDKENTRSSSGLRDAGCPACEMAVVWIQSQLRQ 403

  Fly   300 -------------------NANSEGLFECSSTS-YPDLIININGVDFKIPAKYYIIEEED----- 339
                               :.|.|...:||..| .|.:...|.|..|.:..:.|:::..:
plant   404 NMTQERIVNYINEICERMPSPNGESAVDCSQLSKMPTVSFTIGGKVFDLAPEEYVLKIGEGPVAQ 468

  Fly   340 ----FCSLAIQSINQDFWIMGDVFLGRIYTEFDVGNQRLGFA 377
                |.:|.|.......||:||||:|:.:|.||.||:::|||
plant   469 CISGFTALDIPPPRGPLWILGDVFMGKYHTVFDFGNEQVGFA 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgcl	NP_525030.1	pepsin_retropepsin_like	67..378	CDD:299705	139/432 (32%)
Pgcl	NP_525030.1	Asp	76..379	CDD:278455	136/425 (32%)
AT1G62290	NP_001031219.1	PLN03146	7..>143	CDD:178691	34/61 (56%)
		phytepsin	79..511	CDD:133162	139/432 (32%)
		SapB_2	322..355	CDD:397523	3/32 (9%)
		SapB_1	387..422	CDD:398724	3/34 (9%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.890