Protein Alignment Pgcl and ctsd

DIOPT Version :10

• Sequence 1: NP_525030.1
• Gene: Pgcl / 30984
• FlyBaseID: FBgn0011822
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_571785.2
• Gene: ctsd / 65225
• ZFINID: ZDB-GENE-010131-8
• Length: 398
• Species: Danio rerio
• Alignment Length: 399
• Identity: 160/399 - (40%)
• Similarity: 218/399 - (54%)
• Gaps: 30/399 - (7%)

  Fly     9 LVFLAGLIVLVGEANSTLRRIPIQKSPNFK-------RSHKNIVAERDFVQQKYNRQYTANGYPM 66
            :.||. |:|.....:..:.|||::|....:       ||.:.:|:..:.:  |||..:.|:..|.
Zfish     3 IAFLL-LVVAFFCTSDAIVRIPLKKFRTLRRTLSDSGRSLEELVSSSNSL--KYNLGFPASNDPT 64

  Fly    67 -EHLSNYDNFQYYGNISIGTPGQDFLVQFDTGSSNLWVPGSSCIST--ACQDHQVFYKNKSSTYV 128
             |.|.||.:.||||.|.:|||.|.|.|.|||||||||||...|..|  ||..|..:...||||||
Zfish    65 PETLKNYLDAQYYGEIGLGTPVQTFTVVFDTGSSNLWVPSVHCSLTDIACLLHHKYNGGKSSTYV 129

  Fly   129 ANGTAFSITYGTGSVSGYLSVDCVGFAGLTIQSQTFGEVTTEQGTNFVDAYFDGILGMGFPSLAV 193
            .|||.|:|.||:||:|||||.|......:.::.|.|||...:.|..|:.|.|||||||.:|.:||
Zfish   130 KNGTQFAIQYGSGSLSGYLSQDTCTIGDIAVEKQIFGEAIKQPGVAFIAAKFDGILGMAYPRIAV 194

  Fly   194 DGVTPTFQNMMQQGLVQSPVFSFFLRDNGSVTFYGGELILGGSDPSLYSGSLTYVNVVQAAYWKF 258
            |||.|.|..||.|..|:..||||:|..|.. |..||||:|||:||..|:|...||::.:.|||:.
Zfish   195 DGVPPVFDMMMSQKKVEKNVFSFYLNRNPD-TQPGGELLLGGTDPKYYTGDFNYVDISRQAYWQI 258

  Fly   259 QTDYIKVGS--TSISTFAQAIADTGTSLIIAPQAQYDQISQLFNA----NSEGLFECSST-SYPD 316
            ..|.:.:||  :......:||.|||||||..|.|:...:.:...|    ..|.:.:|... :.|.
Zfish   259 HMDGMSIGSGLSLCKGGCEAIVDTGTSLITGPAAEVKALQKAIGAIPLMQGEYMVDCKKVPTLPT 323

  Fly   317 LIININGVDFKIPAKYYIIEE----EDFC-----SLAIQSINQDFWIMGDVFLGRIYTEFDVGNQ 372
            :..::.|..:.:..:.||::|    .|.|     .|.|.......||:||||:|:.||.||..|.
Zfish   324 ISFSLGGKVYSLTGEQYILKESQGGHDICLSGFMGLDIPPPAGPLWILGDVFIGQYYTVFDRENN 388

  Fly   373 RLGFAPVNS 381
            |:|||...|
Zfish   389 RVGFAKAKS 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgcl	NP_525030.1	Asp	76..379	CDD:394983	139/320 (43%)
ctsd	NP_571785.2	A1_Propeptide	21..44	CDD:462326	6/22 (27%)
		Cathepsin_D2	70..394	CDD:133157	140/324 (43%)