Protein Alignment Pgcl and Napsa

DIOPT Version :9

• Sequence 1: NP_525030.1
• Gene: Pgcl / 30984
• FlyBaseID: FBgn0011822
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_113858.1
• Gene: Napsa / 60575
• RGDID: 61940
• Length: 420
• Species: Rattus norvegicus
• Alignment Length: 408
• Identity: 157/408 - (38%)
• Similarity: 219/408 - (53%)
• Gaps: 57/408 - (13%)

  Fly    16 IVLVG--EANSTLRRIPIQK--------SPNFKRSHKNIVAERDFVQQKYNRQYTANG----YPM 66
            :||:|  |..:||.|:|:::        ||.:....:          .:.:|..|:.|    .|
  Rat    12 LVLLGNLEPAATLIRVPLRRIHPGHRIFSPLYGWEQR----------AELSRTPTSGGKTAFVP- 65

  Fly    67 EHLSNYDNFQYYGNISIGTPGQDFLVQFDTGSSNLWVPGSSC--ISTACQDHQVFYKNKSSTYVA 129
              ||.:.|.||:|:|.:|||.|:|.|.|||||||||||.:.|  .|.||..|..|....||::..
  Rat    66 --LSKFMNTQYFGDIGLGTPPQNFTVVFDTGSSNLWVPSTRCHFFSLACWFHHRFNPKASSSFRP 128

  Fly   130 NGTAFSITYGTGSVSGYLSVDCVGFAGLTIQSQTFGEVTTEQGTNFVDAYFDGILGMGFPSLAVD 194
            |||.|:|.||||.:||.||.|.:...|:...|.||||...|....|..|.||||||:|||:|||.
  Rat   129 NGTKFAIQYGTGRLSGILSRDNLTIGGIHNVSVTFGEALWEPSLVFALARFDGILGLGFPTLAVG 193

  Fly   195 GVTPTFQNMMQQGLVQSPVFSFFL-RDN-GSVTFYGGELILGGSDPSLYSGSLTYVNVVQAAYWK 257
            ||.|....:::|.|::.|||||:| ||: ||   .||||:||||||..|...||::.|...|||:
  Rat   194 GVQPPLDALVEQRLLEKPVFSFYLNRDSEGS---DGGELVLGGSDPDHYVPPLTFIPVTIPAYWQ 255

  Fly   258 FQTDYIKVGSTSISTFAQ---AIADTGTSLIIAPQAQYDQISQLFNA----NSEGLFECSS-TSY 314
            .....:||| |.::..||   ||.|||||||..|..:...:::....    ..:.|.:||. ...
  Rat   256 VHMQSVKVG-TGLNLCAQGCGAILDTGTSLITGPSEEIRALNKAVGGFPLLTGQYLIQCSKIPEL 319

  Fly   315 PDLIININGVDFKIPAKYYIIE----EEDFCSLAIQSIN-----QDFWIMGDVFLGRIYTEFDVG 370
            |.:..::.||.|.:..:.|:|:    :...|.|..|:::     ...||:||||||.....||.|
  Rat   320 PTVSFSLGGVWFNLTGQDYVIKILQSDVGLCLLGFQALDIPKPEGPLWILGDVFLGSYVAVFDRG 384

  Fly   371 NQRLGFAPVNSAVGLRKA 388
            ::.:|     ..|||.:|
  Rat   385 DKNIG-----PRVGLARA 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgcl	NP_525030.1	pepsin_retropepsin_like	67..378	CDD:299705	139/331 (42%)
		Asp	76..379	CDD:278455	136/323 (42%)
Napsa	NP_113858.1	pepsin_retropepsin_like	69..395	CDD:299705	139/334 (42%)
		Asp	73..397	CDD:278455	139/332 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.890