Protein Alignment Pgcl and Pga3

DIOPT Version :10

• Sequence 1: NP_525030.1
• Gene: Pgcl / 30984
• FlyBaseID: FBgn0011822
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_068521.1
• Gene: Pga3 / 60372
• RGDID: 621573
• Length: 387
• Species: Rattus norvegicus
• Alignment Length: 392
• Identity: 140/392 - (35%)
• Similarity: 208/392 - (53%)
• Gaps: 35/392 - (8%)

  Fly    10 VFLAGLIVLVGEANSTLRRIPIQKSPNFKRSHKNIVAERDFVQQKYNR--------QYTANGYPM 66
            :::.||:.|    :..|.:||:.|..:.:.:.:.....:|:: :||.|        |........
  Rat     4 LWVLGLVAL----SECLVKIPLMKIKSMRENLRESHMLKDYL-EKYPRSRAHVLLEQRRNPSVTY 63

  Fly    67 EHLSNYDNFQYYGNISIGTPGQDFLVQFDTGSSNLWVPGSSCISTACQDHQVFYKNKSSTYVANG 131
            |.:.||.:..|.|.||||||.|:|.|..|||||:||||...|.|.||..|:||...:|||::.:|
  Rat    64 EPMRNYLDLVYIGTISIGTPPQEFKVVLDTGSSDLWVPSIYCSSPACAHHKVFNPLQSSTFLVSG 128

  Fly   132 TAFSITYGTGSVSGYLSVDCVGFAGLTIQSQTFGEVTTEQGTNFVDAYFDGILGMGFPSLAVDGV 196
            ...::.||:|.:||:|:.|.|....||:.:|.||....|.|.....|.||||||:|:|:|.:.||
  Rat   129 RPVNVAYGSGEMSGFLAYDTVKIGDLTVVAQAFGLSLEEPGRFMEHAVFDGILGLGYPNLGLQGV 193

  Fly   197 TPTFQNMMQQGLVQSPVFSFFLR---DNGSVTFYGGELILGGSDPSLYSGSLTYVNVVQAAYWKF 258
            ||.|.|:..|||:...:|:|:|.   :.|||      |:|||.|||.|.|.|.:|.|.:.:||:.
  Rat   194 TPVFDNLWIQGLIPQNLFAFYLSSKDEKGSV------LMLGGVDPSYYHGELHWVPVSKPSYWQL 252

  Fly   259 QTDYIKVGSTSIST--FAQAIADTGTSLIIAPQAQYDQISQLFNANSEG----LFECSS-TSYPD 316
            ..|.|.:....|:.  ..|.|.||||||:..|::....|..|..|.:.|    ..:|.: .:.||
  Rat   253 AVDSISMNGEIIACDGGCQGIMDTGTSLVTGPRSSILNIQNLIGAKASGDGEYFLKCDTINTLPD 317

  Fly   317 LIININGVDFKIPAKYYIIEEEDF-CSLAIQSINQD-----FWIMGDVFLGRIYTEFDVGNQRLG 375
            ::..|:.|.:.:||..||.::... |....:....|     .|::|||||...:|.||..|.|:|
  Rat   318 IVFTIDSVTYPVPASAYIRKDHSHNCRSNFEESTDDPSDPELWVLGDVFLRLYFTVFDRANNRIG 382

  Fly   376 FA 377
            .|
  Rat   383 LA 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgcl	NP_525030.1	Asp	76..379	CDD:394983	125/318 (39%)
Pga3	NP_068521.1	A1_Propeptide	18..44	CDD:462326	4/26 (15%)
		pepsin_retropepsin_like	64..385	CDD:472175	128/327 (39%)