Protein Alignment Pgcl and cathD

DIOPT Version :9

• Sequence 1: NP_525030.1
• Gene: Pgcl / 30984
• FlyBaseID: FBgn0011822
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_001334713.1
• Gene: cathD / 45268
• FlyBaseID: FBgn0029093
• Length: 392
• Species: Drosophila melanogaster
• Alignment Length: 392
• Identity: 170/392 - (43%)
• Similarity: 223/392 - (56%)
• Gaps: 29/392 - (7%)

  Fly     8 SLVFLAGLIVLVGEANST----LRRIPIQKSPNFKRSHKNIVAERDFVQQKYNRQYTANGYPMEH 68
            :|:.:|.|...|...||.    |.|:|:.|..:.:|...::..|...::.:|     ..|...|.
  Fly     5 ALLLVAFLAAAVAHPNSQEKPGLLRVPLHKFQSARRHFADVGTELQQLRIRY-----GGGDVPEP 64

  Fly    69 LSNYDNFQYYGNISIGTPGQDFLVQFDTGSSNLWVPGSSCIST--ACQDHQVFYKNKSSTYVANG 131
            ||||.:.||||.|:||:|.|:|.|.|||||||||||...|..|  ||..|..:..:||.||..||
  Fly    65 LSNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSKTYTKNG 129

  Fly   132 TAFSITYGTGSVSGYLSVDCVGFAGLTIQSQTFGEVTTEQGTNFVDAYFDGILGMGFPSLAVDGV 196
            |.|:|.||:||:|||||.|.|..|||.|:.|||.|..:|.|..||.|.||||||:|:.|::||.|
  Fly   130 TEFAIQYGSGSLSGYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVAAKFDGILGLGYNSISVDKV 194

  Fly   197 TPTFQNMMQQGLVQSPVFSFFL-RDNGSVTFYGGELILGGSDPSLYSGSLTYVNVVQAAYWKFQT 260
            .|.|..|.:|||:.:|||||:| ||..|..  |||:|.|||||:.|:|..||:.|.:.|||:.:.
  Fly   195 KPPFYAMYEQGLISAPVFSFYLNRDPASPE--GGEIIFGGSDPNHYTGEFTYLPVTRKAYWQIKM 257

  Fly   261 DYIKVGSTSI-STFAQAIADTGTSLIIAPQAQYDQISQLFNANS--EGLFECSSTSYPDL-IIN- 320
            |...:|...: ....|.|||||||||.||..:...|:|......  .|.:..|....|.| :|.
  Fly   258 DAASIGDLQLCKGGCQVIADTGTSLIAAPLEEATSINQKIGGTPIIGGQYVVSCDLIPQLPVIKF 322

  Fly   321 -INGVDFKIPAKYYIIEE---------EDFCSLAIQSINQDFWIMGDVFLGRIYTEFDVGNQRLG 375
             :.|..|::..|.||:..         ..|..|.|...|...||:||||:|:.|||||:||.|:|
  Fly   323 VLGGKTFELEGKDYILRVAQMGKTICLSGFMGLDIPPPNGPLWILGDVFIGKYYTEFDMGNDRVG 387

  Fly   376 FA 377
            ||
  Fly   388 FA 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgcl	NP_525030.1	pepsin_retropepsin_like	67..378	CDD:299705	156/329 (47%)
		Asp	76..379	CDD:278455	151/320 (47%)
cathD	NP_001334713.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455572
Domainoid	1	1.000	97	1.000	Domainoid score	I1884
eggNOG	1	0.900	-	-		E1_KOG1339
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1684
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.900